NIH Extramural Nexus
SPECIAL EDITION March 5, 2008

FROM THE DIRECTOR: On this Nexus Special Edition

Dr. Norka Ruiz BravoDear Extramural Community Members,

With the recent release of NIH's much-anticipated final draft report on peer review and the public comment period closing on March 17, we bring you this special edition of the Nexus to ensure your timely access to the latest news on this important issue.

The "peer review enhancement" effort is part of NIH's longstanding commitment to supporting promising and meritorious biomedical and behavioral research using diverse approaches, strategies and mechanisms. We will keep you abreast of developments in future editions of the Nexus.

Look for a full issue of the March Nexus later this month.

— Norka Ruiz Bravo
OER Director and NIH Deputy Director for Extramural Research

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NIH Director Examining Peer Review Report;
Public Comment Period Closes March 17

The NIH Director Dr. Elias Zerhouni is mulling the final draft of the "NIH 2007-2008 Peer Review Self-Study" submitted Feb. 28, 2008, marking the end of the diagnostic phase of the peer review enhancement effort. The public comment period is open through Monday, March 17, 2008. To access the full report and for details on submitting comments please visit the Enhancing Peer Review at NIH Web site.

Last year, Dr. Zerhouni established two working groups (the Advisory Committee to the Director and the NIH Steering Committee) to examine the peer review system NIH uses to support biomedical and behavioral research. The groups were charged with identifying the most significant challenges and proposing recommendations that would enhance this system in the most transformative manner. During the summer and fall of 2007, both working groups embarked on an in-depth evaluation of peer review that included soliciting input from NIH internal and external communities and extensively deliberating about challenges and recommendations.

The final report reflects the outcome of the diagnostic phase and includes the working groups' recommendations to the most significant challenges facing the peer review system (details of implementation were purposefully omitted during this phase of the project). Dr. Zerhouni will carefully consider the recommendations and work with the Steering Committee Peer Review Implementation Group to develop an implementation plan. NIH will formally announce the new initiatives it plans to implement in the spring of 2008.

Below are the challenges the report identified with some of the recommendations for addressing each of them:

Reduce Administrative Burden on Applicants, Reviewers, and NIH Staff

  • Recommendations: Reduce application length but emphasize their impact/uniqueness/originality; consider all applications as new, eliminating special status of amended applications; establish "Not Recommended for Resubmission (NRR)" to help applicants make faster, more informed decisions to either refine an existing application or develop a new idea.

Enhance the Rating System

  • Recommendations: Provide unambiguous feedback to applicants by modifying the rating system to provide an independent overall score and ranking; rate multiple, explicit criteria individually.

Enhance Review and Reviewer Quality

  • Recommendations: Enhance training for reviewers, study sections and Scientific Review Officers; create more flexible service and deadlines for reviewer grant submissions; analyze patterns of participation by clinician scientists in peer review and provide more flexibility to ensure their continued involvement in review.

Optimize Support for Different Career Stages and Types

  • Recommendations: Continue to fund more R01s for early-career investigators to be on par with established investigators in application success rates; enhance productivity of the most accomplished investigators by refining mechanisms, such as MERIT/Javits, etc.; pilot the review of early-career investigators using generalists as reviewers to encourage risk-taking and innovation or uniqueness among applicants.

Optimize Support for Different Types and Approaches of Science

  • Recommendations: Use award programs, such as Pioneer, New Innovator and EUREKA, as starting points to invite, identify and support transformative research; ensure participation of adequate numbers of clinician scientists by providing more flexible options for review service; employ editorial board models for the review of interdisciplinary research that includes content experts and big-picture thinkers.

Reduce the Stress on the Support System of Science

  • Recommendations: Establish a "minimum-percent effort" for investigators on research project grants to ensure optimal use of NIH resources; analyze the NIH contribution for optimal biomedical workforce needs.

Meet the Need for Continuous Review of Peer Review

  • Recommendations: Establish a periodic, data-driven, NIH-wide assessment of the peer review process; capture appropriate current baseline data; develop new metrics to track key elements of the peer review system.

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Department of Health and Human Services (HHS)National Institutes of Health (NIH)

 

NIH Office of Extramural Research


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