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Effect of Exercise on Prevention of Weight Gain
This study has been completed.
Sponsors and Collaborators: University of Pittsburgh
National Institutes of Health (NIH)
Information provided by: University of Pittsburgh
ClinicalTrials.gov Identifier: NCT00177502
  Purpose

The purpose of this study is to examine the dose-response of exercise on prevention of weight gain in overweight adults.


Condition Intervention Phase
Weight Loss
Behavioral: behavioral exercise intervention
Phase I
Phase II

MedlinePlus related topics: Exercise and Physical Fitness Weight Control
U.S. FDA Resources
Study Type: Interventional
Study Design: Prevention, Randomized, Open Label, Active Control, Single Group Assignment
Official Title: Effect of Exercise on Prevention of Weight Gain

Further study details as provided by University of Pittsburgh:

Primary Outcome Measures:
  • body weight

Secondary Outcome Measures:
  • fitness
  • physical activity
  • dietary intake
  • mediators

Estimated Enrollment: 294
Study Start Date: January 2003
Estimated Study Completion Date: December 2006
  Eligibility

Ages Eligible for Study:   18 Years to 55 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  1. Female or Male
  2. 18-55 years of age
  3. BMI = 25-29.9 kg/m2
  4. Ability to provide informed consent.
  5. Ability to provide consent from their personal physician to participate in this study.

Exclusion Criteria:

  1. Reporting regular exercise participation of at least 20 minutes per day on at least 3 days per week during the previous six months. (This study is designed to recruit relatively sedentary adults.)
  2. Diabetes, hypothyroidism, or other medical conditions which would affect energy metabolism.
  3. Women who are currently pregnant, pregnant within the previous six months, or planning on becoming pregnant within the next 12 months. (Pregnancy during initial screening will be based on self-report and will be included on the detailed medical history that is completed by subjects. However, this will be confirmed with the urine pregnancy test that will be conducted prior to the baseline DEXA.)
  4. Non-medicated resting systolic blood pressure >160 mmHg or non-medicated resting diastolic blood pressure >100 mmHg, or taking medication that would affect blood pressure.
  5. Taking medication that would affect resting heart rate or the heart rate response during exercise (e.g., beta blockade).
  6. Arrhythmia on resting or exercise electrocardiogram that would indicate that vigorous exercise was contraindicated.
  7. History of myocardial infarction or valvular disease.
  8. History of orthopedic complications that would prevent optimal participation in the exercise component (e.g., heel spurs, severe arthritis).
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00177502

Locations
United States, Pennsylvania
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15203
Sponsors and Collaborators
University of Pittsburgh
Investigators
Principal Investigator: John M Jakicic, Ph.D. University of Pittsburgh
  More Information

Study ID Numbers: R01 HL070257-01A1, R01 HL070257-01A1
Study First Received: September 12, 2005
Last Updated: September 12, 2005
ClinicalTrials.gov Identifier: NCT00177502  
Health Authority: United States: Institutional Review Board

Study placed in the following topic categories:
Body Weight
Signs and Symptoms
Weight Loss
Body Weight Changes
Weight Gain

ClinicalTrials.gov processed this record on January 16, 2009