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National Cancer Institute U.S. National Institutes of Health
Tools & Resources


KinCohort is a MATLAB software package for likelihood-based analysis of kin-cohort data.

Download KinCohort

Readme text

  1. Download the zip file and unpack it in an appropriate directory.
  2. In MATLAB, use the (file--> set path) menu to add the directory to the search path in which the files have been placed.
  3. The main user interface programs are:
    • 'pexpsurv_kk' which produces the kin-cohort estimate of survival curves, and
    • 'bspexpsurv_kk' which produces bootstrap estimates of the survival curves.
  4. Both of these functions have been annotated to explain the input and output arguments.

License Agreement

Suggested reference for the KinCohort program:

  • A marginal likelihood approach for estimating penetrance from kin-cohort designs. Chatterjee N and Wacholder S. Biometrics. 2001 Mar;57(1):245-52.

See also:

  • The kin-cohort study for estimating penetrance. Wacholder et al. Am J Epidemiol. 1998 Oct 1;148(7):623-30.
  • Pseudo-likelihood estimates of the cumulative risk of an autosomal dominant disease from a kin-cohort study. Moore et al. Genet Epidemiol. 2001 Feb;20(2):210-27.

Questions? Contact: Nilanjan Chatterjee