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Fundamentals
On a multi-PI application, you need to act as a full-fledged PI.
Science drives the decision for choosing multiple PIs.
You may forfeit your status as a new PI.

Contact your program officer early.

As a new investigator, you may consider a multiple PI application as an entree into NIH funding.

The appeal: you can join a group of experienced investigators, and you will not have to write an entire application.

But beware. The choice is demanding, and we often caution against it. Read the caveats below.

  • Is it appropriate?
    • A multiple PI application is for collaborative projects with distinct subprojects that address a core objective or theme.
    • As a full-fledged principal investigator, you must be fully in charge of at least one research aim, and your project must be significant enough to stand on its own.
  • You may lose new investigator status.
    • For most award types, you no longer qualify as "new" after the project is funded. For a list of exceptions, see Are You "New"?
    • As part of a multiple PI application, you are not "new" unless all the other PIs also meet NIH's new investigator definition.
  • It can be harder to succeed in peer review.

Contact your program officer early on to discuss whether the multi-PI approach is appropriate and beneficial for you.

For details, read Take Heed -- You Might Want to Avoid a Multiple PI Application in the NIH Grant Cycle: Application to Renewal.

Find more information online:

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