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PET RADIOCHEMISTRY FACILITY. The new NIMH PET radiochemistry facility is directed by Victor Pike, PhD. This laboratory is fully equipped for medicinal and radiochemistry, including six hot cells, extensive HPLC, LC-MS, GC-MS, 400 MHz NMR, three 11C and one 18F automated synthesis apparatus. Each hot cell is connected to each of three cyclotrons located in an adjacent vault.

PET IMAGING. PET IMAGING. The NIH PET Department has three GE Advance PET cameras and a Siemens High Resolution Research Tomograph. In addition, a rodent PET device (ATLAS) constructed in-house by Mike Green is available for in vivo imaging of rats and mice at the NIH Mouse Imaging Facility (MIF). NIMH recently purchased two new PET cameras to image rodents (Siemens microPET Focus 120) and monkeys (Siemens microPET Focus 220).

The branch receives a full range of support, from personnel to equipments, from the Clinical Center.

MR IMAGING. Most MRI/fMRI studies will be carried out on the 3 Tesla magnet at the 3T Functional Neuroimaging Facility. Some studies may also be performed on the NIH MRI Research Facility. A 7-Tesla small animal MR scanner is also available at MIF

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