In adults the best equation for estimating glomerular filtration rate (GFR) from serum creatinine is the Modification of Diet in Renal Disease (MDRD) Study equation. The calculators below are to be used when Scr is in µmol/L.
IDMS-Traceable MDRD Study Equation1
NOTE: This equation should be used only with those creatinine methods that have been recalibrated to be traceable to IDMS. For more information about recalibration, visit NKDEP's Laboratory Professionals section.
GFR (mL/min/1.73 m2) = 175 x (Scr/88.4)-1.154 x (Age)-0.203 x (0.742 if female) x (1.212 if African American) (SI units)
The equation does not require weight because the results are reported normalized to 1.73 m2 body surface area, which is an accepted average adult surface area.
1 Levey AS, Coresh J, Greene T, Stevens LA, Zhang YL, Hendriksen S, Kusek JW, Van Lente F; Chronic Kidney Disease Epidemiology Collaboration. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med. 2006 Aug 15;145(4):247–54.