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Home > Health Professionals > GFR Calculators > GFR MDRD Calculators for Adults (Conventional units)
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GFR MDRD Calculators for Adults (Conventional units)

In adults the best equation for estimating glomerular filtration rate (GFR) from serum creatinine is the Modification of Diet in Renal Disease (MDRD) Study equation.

Original MDRD Study Equation1,2

NOTE: This equation should be used only with those creatinine methods that have not been recalibrated to be traceable to IDMS. For more information about recalibration, visit NKDEP's Laboratory Professionals section.

GFR (mL/min/1.73 m2) = 186 x (Scr)-1.154 x (Age)-0.203 x (0.742 if female) x (1.212 if African-American) (conventional units)

The equation does not require weight because the results are reported normalized to 1.73 m2 body surface area, which is an accepted average adult surface area.

Plasma creatinine (mg/dL)
Age*
African American Yes No
Gender Male Female
 
GFR value: mL/min/1.73 m2**
*This equation should only be used for patients 18 and older.

**The NKDEP presently recommends reporting estimated GFR values greater than or equal to 60 mL/min/1.73 m2 simply as "≥60 mL/min/1.73 m2", not an exact number.

1 Levey AS, Greene T, Kusek J, and Beck G. A simplified equation to predict glomerular filtration rate from serum creatinine (abstract). J Am Soc Nephrol. 2000. 11: p.155A.
2 Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med. 1999 Mar 16;130(6):461–70.


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Last Reviewed: December 19, 2007

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