| Topic: | digestive diseases (dd) |
| Title: | Surface Imaging in Barrett’s Esophagus: The Role of High-Resolution Endoscopy, Magnifying Endoscopy, and Related Techniques. |
| Author: | Sharma, P.; Kara, M.A.; Bergman, J.J.G.H.M. |
| Source: | IN: Sharma, P.; Sampliner, R., eds. Barrett’s Esophagus and Esophageal Adenocarcinoma. 2nd ed. Williston, VT: Blackwell Publishing Inc. 2006. pp 149-155. |
| Availability: | Available from Blackwell Publishing Inc. P.O. Box 20, Williston, VT 05495. Phone: 1-800-216-2522. Email: orders@aidcvt.com. Website: www .blackwellpublishing.com. Price: $169.95. |
| Abstract: | This textbook chapter focuses on the use of surface imaging and endoscopy for surveillance in patients who have been diagnosed with Barrett’s esophagus, the premalignant lesion for adenocarcinoma of the esophagus. The authors focus on the role of high-resolution endoscopy, magnifying endoscopy, and related techniques. They note that because malignancy develops in a standard sequence—metaplasia to dysplasia to cancer—the goal of surveillance is to diagnose and treat dysplasia or early cancer and thus prevent the development of advanced cancer, which is associated with a poor prognosis. They discuss high-resolution endoscopy, magnifying endoscopy, techniques that can enhance high-resolution and magnifying endoscopy, acetic acid chromoendoscopy, indigo carmine chromoendoscopy, methylene blue chromoendoscopy, narrow band imaging, and determining which dye or technique to use. Magnifying endoscopy enables the detection of abnormalities of the surface mucosal and vascular pattern, resulting in the distinction of early abnormalities that may accompany neoplastic transformation. Chromoendoscopy with various staining agents may further enhance the surface structure; however, it is labor-intensive and operator-dependent for best results. 24 references. |
| Format: | Book Chapter |
| Language: | English. |
| Major Keywords: | Digestive System Diseases. Barretts Esophagus. Cancer. Esophagus. Cytology. Histology. Endoscopy. Pathology. Diagnostic Tests. |
| Minor Keywords: | Patient Selection. Dysplasia. Symptoms. Risk Factors. Pathogenesis. Diagnosis. Screening. Neoplasms. Mucosal Tissue. |
| Publication Number: | DDBK10789. |
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