Biography

Dr. Mbulaiteye received his M.D. from Makerere University, Kampala, in 1990, an MPhil in Epidemiology and Biostatistics from Cambridge University in 1994 and a Masters in Internal Medicine from Makerere University in 1996. He worked as a Senior Registrar at the Uganda Cancer Institute and a Project Medical Officer in the Medical Research Council Programme for AIDS in Uganda before joining NCI as a Research Fellow in 2000. He became a tenure-track investigator in 2005. He is a member of the Uganda National Academy of Sciences, the African Organization for Research and Training in Cancer (AORTIC), Darwin College Society, and Cambridge Common Wealth Trust. Currently, he serves on the DCEG Technical Evaluation of Questionnaires, NIH Tenure-Track Investigators Committee, and is an adjunct lecturer at George Washington University School of Public Health. He was a recipient of the NCI Directors Investigator Innovation Award in 2008 and the NIH Award of Merit in 2008.

Research Interests

Dr. Mbulaiteye’s research is centered on using epidemiologic study methods to investigate infectious, immunological, and genetic co-factors associated with two human ?-herpesvirus-associated malignancies, namely Burkitt lymphoma, which is associated with Epstein-Barr virus (EBV), and Kaposi sarcoma, which is associated with human herpesvirus 8 (HHV-8.

Projects:

• Case-control study of Burkitt lymphoma in East Africa (cross link to non-AIDS lymphoma)
• Human herpesvirus 8 and Kaposi sarcoma epidemiology in Ugandan and other populations (cross link to Kaposi sarcoma and KS herpesvirus)
• HIV/AIDS Cancer Match Study in Uganda (cross link to HIV/AIDS malignancies)

Keywords

Human herpesvirus 8 (HHV-8), Epstein-Barr virus, Kaposi sarcoma, lymphoma, AIDS, immunosuppression, chimerism, gastric cancer, epidemiology, genetic risk, Africa

Selected Publications

• Ogwang MD, Bhatia K, Biggar RJ, Mbulaiteye SM. Incidence and geographic distribution of endemic Burkitt lymphoma in northern Uganda revisited. Int J Cancer 2008, 123:2658-63.
• Guech-Ongey M, Engels EA, Goedert JJ, Robert RJ. Biggar and Mbulaiteye SM. Risk of squamous cell carcinoma of the conjunctiva and other ocular cancers among adults with AIDS in the United States. Int J Cancer 2008; 122:2590.
• Mbulaiteye, S.M., Katabira, E. T., Wabinga, H., Parkin, D. M., Virgo, P., Ochai, R., Workneh, M., Coutinho, A., and Engels, E. A. Spectrum of cancers among HIV-infected persons in Africa: the Uganda AIDS-Cancer Registry Match Study. Int J Cancer. 2006; 118: 985-990.
• Carpenter LM, Newton R, Casabonne D, Ziegler J, Mbulaiteye S, Mbidde E, Wabinga H, Jaffe H, Beral V. Antibodies against malaria and Epstein-Barr virus in childhood Burkitt lymphoma: a case-control study in Uganda.. Int J Cancer 2008; 122:1319-23.
• Mbulaiteye SM, Biggar, R. J., Bakaki, P. M., Pfeiffer, R. M., Whitby, D., Owor, A. M., Katongole-Mbidde, E., Goedert, J. J., Ndugwa, C. M., and Engels, E. A. Human herpesvirus 8 infection and transfusion history in children with sickle-cell disease in Uganda. J Natl Cancer Inst, 2003; 95: 1330-1335.

Collaborators

DCEG Collaborators

• Robert J. Biggar, M.D., Eric A. Engels, M.D., Anil Chaturvedi, Ph.D., Charles S. Rabkin, M.D., James J. Goedert, M.D., Ruth M. Pfeiffer, Ph.D., Steven Chanock, M.D.

Other NCI Collaborators

• Kishor Bhatia, Ph.D., MRC Path.

Other Scientific Collaborators

• Mohammed R. Moosa, M.D., University of Stellenbosch, Cape Town, South Africa
• Johann Schneider, M.D., University of Stellenbosch, Cape Town, South Africa
• Glen R. Brubaker, M.D., Interchurch Mission/Shirati Hospital, Tanzania
• Martin D. Ogwang, St. Mary’s Hospital, Lacor, Gulu, Uganda
• Patrick Kerchan, MBchB, Kuluva Hospital, Arua, Uganda
• Esther Kawira, M.D., Shirati Health Education and Development Foundation, Shirati, Tanzania
• N. A. Othieno Abinya, MBchB, M.Med, Nairobi, Kenya
• Henry Wabinga, MB ChB, Kampala Cancer Registry, Kampala, Uganda
• Martin M. Nsubuga, MRCP, Nsambya Hospital, Kampala, Uganda