Agent Name |
Propyleneimine |
Alternative Name |
2-Methylaziridine |
CAS Number |
75-55-8 |
Formula |
C3-H7-N |
Major Category |
Nitrogen Compounds |
Synonyms |
1,2-Propyleneimine; 1,2-Propylenimine; 2-Methylazacyclopropane; 2-Methylaziridine; 2-Methylethylenimine; Aziridine, 2-methyl-; Methylaziridine; Methylethylenimine; Propilenimina [Spanish]; Propylene imine; Propyleneimine; Propylenimine; [ChemIDplus] UN1921 |
Category |
Other Nitrogen Compounds |
Description |
Colorless, oily liquid with an ammonia-like odor; [NIOSH] |
Sources/Uses |
Used as an intermediate in the rubber and pharmaceutical industries; Used as a modifier and monomer in advanced composites; [HSDB] |
Comments |
At higher concentrations, may cause blistering and necrosis of the skin; Toxicity is similar to that of ethyleneimine; Causes severe injuries to the kidneys (tubular necrosis) in acute animal experiments and tumors in chronic ones; [HSDB] An irritant of the the skin, eyes, and respiratory tract; [ICSC] |
Exposure Assessment |
Skin Designation (ACGIH) |
Yes |
TLV (ACGIH) |
2 ppm |
PEL (OSHA) |
2 ppm |
IDLH (NIOSH) |
100 ppm |
Excerpts from Documentation for IDLHs |
It has been reported that rats survived a 2�hour exposure to 500 ppm and guinea pigs survived a 30�minute exposure to 500 ppm [Carpenter et al. 1948]. |
Vapor Pressure |
112 mm Hg |
Lethal Concentration |
LCLo (rats) = 500 ppm/4 hr |
Explanatory Notes |
See 2008 Notice of Intended Changes; [ACGIH] Flash point = -3 deg C; |
Adverse Effects |
Toxic Pneumonitis |
Yes |
Dermatotoxin |
Skin Burns |
Nephrotoxin |
Yes |
IARC Carcinogen |
Possible Carcinogen |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: PROPYLENEIMINE
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