| Agent Name |
Propyleneimine |
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| Alternative Name |
2-Methylaziridine |
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| CAS Number |
75-55-8 |
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| Formula |
C3-H7-N |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
1,2-Propyleneimine; 1,2-Propylenimine; 2-Methylazacyclopropane; 2-Methylaziridine; 2-Methylethylenimine; Aziridine, 2-methyl-; Methylaziridine; Methylethylenimine; Propilenimina [Spanish]; Propylene imine; Propyleneimine; Propylenimine; [ChemIDplus] UN1921 |
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| Category |
Other Nitrogen Compounds |
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| Description |
Colorless, oily liquid with an ammonia-like odor; [NIOSH] |
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| Sources/Uses |
Used as an intermediate in the rubber and pharmaceutical industries; Used as a modifier and monomer in advanced composites; [HSDB] |
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| Comments |
At higher concentrations, may cause blistering and necrosis of the skin; Toxicity is similar to that of ethyleneimine; Causes severe injuries to the kidneys (tubular necrosis) in acute animal experiments and tumors in chronic ones; [HSDB] An irritant of the the skin, eyes, and respiratory tract; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Yes |
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| TLV (ACGIH) |
2 ppm |
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| PEL (OSHA) |
2 ppm |
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| IDLH (NIOSH) |
100 ppm |
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| Excerpts from Documentation for IDLHs |
It has been reported that rats survived a 2�hour exposure to 500 ppm and guinea pigs survived a 30�minute exposure to 500 ppm [Carpenter et al. 1948]. |
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| Vapor Pressure |
112 mm Hg |
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| Lethal Concentration |
LCLo (rats) = 500 ppm/4 hr |
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| Explanatory Notes |
See 2008 Notice of Intended Changes; [ACGIH] Flash point = -3 deg C; |
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| Adverse Effects |
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| Toxic Pneumonitis |
Yes |
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| Dermatotoxin |
Skin Burns |
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| Nephrotoxin |
Yes |
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| IARC Carcinogen |
Possible Carcinogen |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: PROPYLENEIMINE
|
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