Skip Navigation

HazMap: Occupational Exposure to Hazardous Agents
HazMap Home SIS Home NLM Home

as Search Agents Search Diseases Search Jobs Full Text Search


Haz-Map Home on-tab Custom Search on-tab Help on-tab Web Glossary on-tab Reference on-tab
left corner Browse Haz-Map
right corner
Agent Name Acetophenone
CAS Number 98-86-2
Formula C8-H8-O
Major Category Other Classes
Synonyms 1-Phenyl-1-ethanone; 1-Phenylethanone; Acetofenon [Czech]; Acetophenon; Acetylbenzene; Acetylbenzol; Benzene, acetyl-; Benzoyl methide; Benzoylmethide; Ethanone, 1-phenyl-; Hypnone; Ketone, methyl phenyl; Methyl phenyl ketone; Phenyl methyl ketone; USAF EK-496; [ChemIDplus] UN 1993
Category Aromatic Ketones
Description Liquid that forms crystals at low temperature; [Merck Index]
Sources/Uses Used in textile coatings; [Olson, p. 543] Used in perfumes for orange blossom odor; Also used in organic synthesis and as a polymerization catalyst for olefins; [Merck Index] Used in the past as an analgesic and anesthetic; [ACGIH] Used as a solvent in plastics and resins and a flavoring agent in foods; [HSDB]
Comments A skin and eye irritant; Can cause CNS depression at high concentrations; [Olson, p. 543] Inhalation of high concentration can cause unconsciousness; [ICSC]
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 10 ppm
Vapor Pressure 0.39 mm Hg
Odor Threshold Low 0.17 ppm
Odor Threshold High 0.6 ppm
Lethal Concentration LC (rats) = >210 ppm/8h
Explanatory Notes Odor Threshold avg = 0.5 ppm. [CHEMINFO] mp = 20.5 deg C; bp = 202 deg C; Flash point = 105 deg C; [Merck Index]
Adverse Effects
Neurotoxin CNS Solvent Syndrome
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: ACETOPHENONE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





Specialized Information Services   U.S. National Library of Medicine,
8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health
Privacy/Disclaimer Notice
Customer Service: tehip@teh.nlm.nih.gov
Last updated: January, 2009