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Agent Name Butyrolactone
CAS Number 96-48-0
Formula C4-H6-O2
Major Category Solvents
Synonyms 1,2-Butanolide; 1,4-Butanolide; 2(3H)-Furanone, dihydro-; 2-Oxolanone; 3-Hydroxybutyric acid lactone; 4-Butanolide; 4-Butyrolactone; 4-Deoxytetronic acid; 4-Hydroxybutanoic acid lactone; 4-Hydroxybutyric acid lactone; 6480; Agrisynth BLO; BLO; BLON; Butanoic acid, 4-hydroxy-, gamma-lactone; Butyric acid lactone; Butyric acid, 4-hydroxy-, gamma-lactone; Butyrolactone; Butyryl lactone; Butyrylactone; C-1070; Dihydro-2(3H)-furanone; Dihydro-2-furanone; GBL; No Go; Tetrahydro-2-furanone; gamma-6480; gamma-BL; gamma-Butyrolactone (natural); gamma-Hydroxybutyric acid cyclic ester; gamma-Hydroxybutyric acid lactone; gamma-Hydroxybutyrolactone; [ChemIDplus]
Category Other Solvents
Description Colorless, oily liquid with a pleasant odor; [CAMEO]
Sources/Uses Used as a chemical intermediate, nematicide, and paint and nail polish remover; Also used as a solvent for polymers, inks, cosmetics, and drugs; [HSDB]
Comments Inhalation of butyrolactone produces anesthesia in experimental animals; [HSDB] An eye irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]
Exposure Assessment
Skin Designation (ACGIH) Not evaluated
Vapor Pressure 0.45 mm Hg
Explanatory Notes Flash point = 209 deg F;
Flammability (NFPA) 2: high ambient temperature required
Adverse Effects
Neurotoxin CNS Solvent Syndrome
IARC Carcinogen Not Classifiable
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: BUTYROLACTONE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





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Last updated: January, 2009