| Agent Name |
1,1,2-Trichloroethane |
|---|
| CAS Number |
79-00-5 |
|---|
| Formula |
C2-H3-Cl3 |
|---|
| Major Category |
Solvents |
|---|
| Synonyms |
Ethane trichloride; beta-Trichloroethane; Vinyl trichloride; [NIOSH] UN8027 |
|---|
| Category |
Chlorinated Aliphatic |
|---|
| Description |
Colorless liquid with a sweet, chloroform-like odor; [NIOSH] |
|---|
| Sources/Uses |
Used primarily for synthesis of vinylidene chloride; also used as a solvent in pharmaceutical manufacturing; [ACGIH] Used in lacquers, adhesives, and resins; [HSDB] |
|---|
| Comments |
Acute animal studies: narcosis, anesthesia, and injury to the liver and kidneys; [ACGIH] |
|---|
| Exposure Assessment |
|---|
| Skin Designation (ACGIH) |
Yes |
|---|
| TLV (ACGIH) |
10 ppm |
|---|
| PEL (OSHA) |
10 ppm |
|---|
| MAK |
10 ppm |
|---|
| IDLH (NIOSH) |
100 ppm |
|---|
| Excerpts from Documentation for IDLHs |
Basis for original (SCP) IDLH: The chosen IDLH is based on the UCC [1972] report that 500 ppm killed 1 of 6 rats in 4 hours, and 4 of 6 rats in 8 hours. . . . Human data: None relevant for use in determining the revised IDLH. |
|---|
| Vapor Pressure |
19 mm Hg |
|---|
| Odor Threshold Low |
0.5 ppm |
|---|
| Odor Threshold High |
167 ppm |
|---|
| Lethal Concentration |
LCLo (rats) = 500 ppm/4H |
|---|
| Explanatory Notes |
Odor threshold from "Quick Guide: The Electronic NIOSH Pocket Guide to Chemical Hazards"; |
|---|
| Reference Link |
ATSDR ToxFAQs - 1,1,2-Trichloroethane |
|---|
| Flammability (NFPA) |
1: must be preheated |
|---|
| Adverse Effects |
|---|
| Neurotoxin |
CNS Solvent Syndrome |
|---|
| Hepatotoxin |
Hepatotoxin, Secondary |
|---|
| IARC Carcinogen |
Not Classifiable |
|---|
| Links to Other NLM Databases |
|---|
| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 1,1,2-TRICHLOROETHANE
|
|---|
|
|
