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Cooperative Program in Translational Research for Neuromuscular Disease (U01)
Release Date: August 5, 2008
Announcement Number: PAR-08-229
Application Receipt Date:
October 5, 2008
February 5, 2009
June 5, 2009
October 5, 2009
February 5, 2010
June 5, 2010
October 5, 2010
February 5, 2011
June 5, 2011
Funding Contact: John Porter, Ph.D.
Program Area: Neurogenetics
Brief Description:
The goal of this funding opportunity announcement (FOA), from the National Institute of Neurological Disorders and Stroke
(NINDS) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), is to support preclinical development
and testing of new therapies for neuromuscular diseases. The program will facilitate solicitation, development, and review
of therapy-directed projects to accelerate the translation of basic research discoveries into therapeutic candidates for clinical
testing. This program is specifically directed at projects that include therapeutic leads with demonstrated activity against
the intended disease target. The program supports preclinical optimization and testing of these leads and projects must be
sufficiently advanced that an IND or IDE application to the FDA can be submitted by the end of the project period. The program
does not support early-stage therapeutic discovery activities such as high throughput screening. The program also excludes
clinical research, basic research, and studies of disease mechanism. This is a milestone-driven cooperative agreement program
involving participation of NIH staff in the development of the project plan and monitoring of research progress.
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