| Agent Name |
Diethyl phthalate |
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| CAS Number |
84-66-2 |
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| Formula |
C12-H14-O4 |
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| Major Category |
Plastics & Rubber |
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| Synonyms |
1,2-Benzenedicarboxylic acid, diethyl ester; Anozol; DEP; DPX-F5384; Di-n-ethyl phthalate; Diethyl 1,2-benzenedicarboxylate; Diethyl o-phenylenediacetate; Diethyl o-phthalate; Diethyl phthalate; Diethylester kyseliny ftalove [Czech]; Estol 1550; Ethyl phthalate; Neantine; Palatinol A; Phthalol; Phthalsaeurediaethylester [German]; Placidol E; Solvanol; Unimoll DA; o-Benzenedicarboxylic acid diethyl ester; o-Bis(ethoxycarbonyl)benzene; [ChemIDplus] UN8027 |
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| Category |
Phthalate Esters |
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| Description |
Colorless to water-white, oily liquid with a very slight, aromatic odor. (pesticide); [NIOSH] |
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| Sources/Uses |
Plasticizer (added to polymers to effect flexibility and/or toughness); also used as an insect repellant and solvent; [ACGIH] Used as a solvent in cellulose acetate, fragrances, and cosmetics; [Merck Index #7371] |
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| Comments |
The heated compound is an irritant to the eyes and respiratory tract; [ACGIH] Allergic contact dermatitis reported; [Kanerva, p. 1144-5] In high-dose reproductive studies of rats and mice, DEHP and other phthalates cause testicular damage to males and increased fetal losses and malformations to pregnant females. [Frazier, p. 350-2] Low toxicity both acute and chronic, but could cause CNS depression if large dose absorbed; [HSDB] |
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| Reference Link |
Contact dermatitis from spectacle frames and hearing aid containing diethyl phthalate (No abstract available) |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
5 mg/m3 |
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| Vapor Pressure |
0.002 mm Hg |
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| Explanatory Notes |
Flash point = 161 deg C; |
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| Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
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| Flammability (NFPA) |
1: must be preheated |
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| Adverse Effects |
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| Skin Sensitizer |
Yes |
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| Reproductive Toxin |
Yes |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: DIETHYL PHTHALATE
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