| Agent Name |
Toluene 2,6-diisocyanate |
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| CAS Number |
91-08-7; 26471-62-5 |
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| Formula |
C9-H6-N2-O2 |
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| Major Category |
Plastics & Rubber |
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| Synonyms |
1,3-Diisocyanato-2-methylbenzene; 2,6-Diisocyanato-1-methylbenzene; 2,6-Diisocyanatotoluene; 2,6-TDI; 2-Methyl-meta-phenylene isocyanate; Benzene, 1,3-diisocyanato-2-methyl-; Benzene, 2,6-diisocyanato-1-methyl-; Isocyanic acid, 2-methyl-meta-phenylene ester; 2,6-Toluene diisocyanate; Tolylene 2,6-diisocyanate; UN 2078; m-Tolylene diisocyanate; meta-Tolylene diisocyanates; [ChemIDplus] |
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| Category |
Diisocyanates |
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| Description |
Colorless to pale-yellow liquid with a sharp, acrid odor; [ACGIH] |
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| Sources/Uses |
Occupational asthma reported in floor varnishers and in workers manufacturing polyurethane foams and elastomers; [Malo] |
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| Comments |
"Most reports on TDI failed to specify which isomer was studied or to define its purity; . . . No important toxicologic distinctions between the 2,4- and 2,6-isomers are recognized." [ACGIH] See "2,4-Toluene diisocyanate." |
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| Reference Link |
Occupational asthma due to isocyanates |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
0.005 ppm |
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| STEL (ACGIH) |
0.02 ppm |
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| Vapor Pressure |
0.02 mm Hg |
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| Explanatory Notes |
See 2008 Notice of Intended Changes. [ACGIH] |
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| Reference Link |
ATSDR Medical Management -Toluene diisocyanate |
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| Adverse Effects |
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| Asthma |
Yes |
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| Toxic Pneumonitis |
Yes |
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| Fibrogenic |
Yes |
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| Dermatotoxin |
Skin Burns |
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| Skin Sensitizer |
Yes |
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| Lacrimator |
Yes |
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| IARC Carcinogen |
Possible Carcinogen |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 2,6-TOLUENE DIISOCYANATE
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