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Agent Name
Isophorone diisocyanate
CAS Number
4098-71-9
Formula
C12-H18-N2-O2
Major Category
Plastics & Rubber
Synonyms
IPDI; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl-isocyanate; Isophorone diamine diisocyanate; [NIOSH]
Category
Diisocyanates
Description
Colorless to slightly yellow liquid with a pungent odor; [NIOSH]
Sources/Uses
Used in polyurethane paints, varnishes, and elastomers; [HSDB] Occupational asthma reported in spray painter; [Malo]
Comments
May cause skin sensitization; [ICSC] See "DIISOCYANATES."
Reference Link
Isophorone diisocyanate induced respiratory disease (IPDI).
Exposure Assessment
Skin Designation (ACGIH)
No
TLV (ACGIH)
0.005 ppm
MAK
0.005 ppm
Vapor Pressure
0.0003 mm Hg
Reference Link
International Chemical Safety Cards (WHO/IPCS/ILO)
Adverse Effects
Asthma
Yes
Skin Sensitizer
Yes
Links to Other NLM Databases
Health Studies
Human Health Effects from Hazardous Substances Data Bank:
ISOPHORONE DIISOCYANATE
Toxicity Information
Search TOXNET
Chemical Information
Search ChemIDplus
Biomedical References
Search PubMed
Related Information in Haz-Map
Diseases
Occupational diseases associated with exposure to this agent:
Asthma, occupational
Contact dermatitis, allergic
Processes
Industrial Processes with risk of exposure:
Painting (Pigments, Binders, and Biocides)
Plastic Composites Manufacturing
Specialized Information Services
U.S. National Library of Medicine
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8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health
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Last updated: January, 2009