| Agent Name |
Titanium tetrachloride |
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| CAS Number |
7550-45-0 |
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| Formula |
Cl4-Ti |
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| Major Category |
Toxic Gases & Vapors |
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| Synonyms |
Tetrachlorotitanium; Tetrachlorure de titane [French]; Titaantetrachloride [Dutch]; Titane (tetrachlorure de) [French]; Titanic chloride; Titanio (tetracloruro di) [Italian]; Titanium chloride; Titanium chloride (TiCl4); Titanium chloride (TiCl4), (T-4)-; Titanium tetrachloride; Titantetrachlorid [German]; [ChemIDplus] UN1838 |
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| Category |
Other Toxic Gases & Vapors |
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| Description |
A colorless fuming liquid with a pungent odor; [CAMEO] |
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| Sources/Uses |
Used to manufacture titanium-containing compounds; used as white pigments in paints; [ATSDR ToxFAQs] Used in chemical vapor deposition to apply coatings to metals and other materials with high melting points--the process involves bubbling hydrogen and nitrogen though a bath of titanium tetrachloride or vanadium tetrachloride. [Scand J Work Environ Health 1991;17:369-79] |
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| Comments |
Can cause pneumonitis; [Table 16.3, Sullivan, p. 213] Liquid causes second degree burns after contact for a few minutes. [CHRIS] Corrosive to skin; [Quick CPC] When TiCl4 comes in contact with water, HCl is rapidly generated. [ATSDR ToxFAQs] See [Park T, et al. Diffuse Endobronchial Polyposis Following A Titanium Tetrachloride Inhalation Injury. Am Rev Respir Dis. 1984 Aug;130(2):315-7] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause pulmonary edema; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| TIH |
Yes |
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| Vapor Pressure |
0.01 mm Hg |
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| Lethal Concentration |
LC50 (rats) = 400 mg/m3 |
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| Reference Link |
ATSDR - ToxFAQs - Titanium Tetrachloride |
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| Flammability (NFPA) |
0: will not burn |
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| Adverse Effects |
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| Toxic Pneumonitis |
Yes |
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| Dermatotoxin |
Skin Burns |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: TITANIUM TETRACHLORIDE
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