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Agent Name
Polymethylene polyphenyl isocyanate
CAS Number
9016-87-9
Major Category
Plastics & Rubber
Synonyms
PAPI; Polymeric diphenylmethane diisocyanate; Isocyanic acid, polymethylenepolyphenylene ester; Polymeric MDI; Polymeric Methylene Diphenyl Diisocyanate; [ChemFinder]
Category
Diisocyanates
Description
Dark amber viscous liquid; [HSDB]
Sources/Uses
This resin is used as a binder in particle board and foundry cores. It is used to make polyurethane elastomers for shoes and automobile bumpers. [HSDB]
Comments
Occupational asthma reported in paint shop worker; [Malo] See "DIISOCYANATES."
Reference Link
Prevalence of occupational asthma in spray painters exposed to several types of isocyanates, including polymethylene polyphenylisocyanate
Exposure Assessment
Skin Designation (ACGIH)
Not evaluated
MAK
0.05 ppm, inhalable fraction
Vapor Pressure
3 x 10
-06
mm Hg
Lethal Concentration
LC50 (rats) = 490 mg/m3/4h
Adverse Effects
Asthma
Yes
IARC Carcinogen
Not Classifiable
Links to Other NLM Databases
Health Studies
Human Health Effects from Hazardous Substances Data Bank:
POLYMETHYLENE POLYPHENYL ISOCYANATE
Toxicity Information
Search TOXNET
Chemical Information
Search ChemIDplus
Biomedical References
Search PubMed
Related Information in Haz-Map
Diseases
Occupational diseases associated with exposure to this agent:
Asthma, occupational
Processes
Industrial Processes with risk of exposure:
Molding and Core Making
Painting (Pigments, Binders, and Biocides)
Plastic Composites Manufacturing
Specialized Information Services
U.S. National Library of Medicine
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8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health
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Last updated: January, 2009