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National Cancer Institute U.S. National Institutes of Health www.cancer.gov
About DCEG

Kiyohiko Mabuchi, M.D., Dr.P.H.

Expert

Location: Executive Plaza South, Room 7038
Phone: 301-594-7649
Fax: 301-402-0207
E-mail: km221v@nih.gov

 Kiyohiko Mabuchi, M.D., Dr.P.H.

Biography

Dr. Mabuchi received an M.D. from Osaka University Medical School, and an M.P.H. / Dr.PH. from the John Hopkins University School of Hygiene and Public Health. He joined the DCEG Radiation Epidemiology Branch in 2000 as Expert after serving as Chief of the Department of Epidemiology at the Radiation Effects Research Foundation, Japan, which is involved in the long-term epidemiological studies of health effects of radiation exposure in cohorts of atomic bob survivors and their children in Hiroshima and Nagasaki. He has been a member of several international radiation committees, including the International Commission of Radiological Protection (ICRP) and the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR), and also formerly a member of the Executive Committee of the International Association of Cancer Registries.

Research Interests

  • Cancer risks associated with exposure to ionizing radiation and how the radiation-related risks are modified by modes of exposure and other factors including age, gender, time as well as host and carcinogenic factors
  • The risk and dose-response for chronic diseases other than cancer associated with exposure to ionizing radiation
  • The risks of melanoma and non-melanoma skin cancers associated with non-ionizing ultraviolet (UV) radiation and how the risks are modified by types of UV exposure and other factors including ionizing radiation exposure and host factors

Selected Publications

  • Hauptmann M, Mohan AK, Doody MM, Linet MS, Mabuchi K: "Mortality from diseases of the circulatory system in U.S. radiologic technologists." Am J Epidemiol 2003;157:239-248.
  • Pierce DA, Sharp GB, Mabuchi K: "Joint effects of radiation and smoking for lung cancer risk among atomic bomb survivors." Radiat Res. 2003;159:511-520.
  • Sharp GB, Mizuno T, Cologne JB, Tokuoka S, Mabuchi K: "Hepatocellular carcinoma among atomic-bomb survivors: Significant interaction of radiation with hepatitis C virus infections." Int J Cancer 2003;103:531-537.
  • Preston DL, Ron E, Yonehara S, Kobuke T, Fujii H, Kishikawa M, Tokuoka S, Mabuchi K: "Tumors of the nervous system and pituitary gland associated with radiation exposure from the atomic bombs." JNCI 2002;94:1555-63.
  • Cologne JB, Tokuoka S, Beebe GW, Fukuhara T, Mabuchi K: "Effects of radiation on incidence of primary liver cancer among atomic bomb sruvivors." Radiat Res 1999;152:364-373.
  • Shimizu Y, Pierce DA, Preston DL, Mabuchi K: "Studies of the mortality of atomic-bomb survivors. Report 12, Part II. Noncancer mortality: 1950-1990." Radiat Res 1999;152:374-389.
  • Ron E, Preston DL, Kishikawa M, Kobuke T, Iseki M, Tokuoka S, Tokunaga M, Mabuchi K: "Skin tumor risk among atomic bomb survivors." Cancer Causes & Control 1998;9:393-401.
  • Delongchamp RR, Mabuchi K, Yoshimoto Y, Preston DL: "Cancer mortality among atomic bomb survivors exposed in utero or as young children, October 1950-May 1992." Radiat Res 1997;147:385-395.
  • Mabuchi K, Ron E, Preston DL: "Cancer Incidence Among Japanese Atomic-Bomb Survivors. In: Implications of New Data on Radiation Cancer Risk (Proceedings of the Thirty-Second Annual Meeting of the National Council on Radiation Protection and Measurements) Ed by Boice JD Jr., National Council on Radiation Protection and Measurements, pp. 41-49, 1997.
  • Pierce DA, Shimizu Y, Preston DL, Vaeth M, Mabuchi K: "Studies of the mortality of atomic bomb survivors. Report 12, Part 1. Cancer: 1950-1990." Radiat Res 1996;146:1-27.
  • Mabuchi K, Soda M, Ron E, Tokunaga M, Ochikubo S, Sugimoto S, Ikeda T, Terasaki M, Preston DL, Thompson DE: "Cancer incidence in atomic bomb survivors. Part I: Use of the tumor registries in Hiroshima and Nagasaki for incidence studies." Radiat Res 1994;137:S1-S16.
  • Thompson DE, Mabuchi K, Ron E, Soda M, Tokunaga M, Ochikubo S, Sugimoto S, Ikeda T, Terasaki M, Izumi S, Preston DL: "Cancer incidence in atomic bomb survivors. Part II: Solid tumor incidence, 1958-87." Radiat Res 1994;137:S17-S67.
  • Preston DL, Kusumi S, Tomonaga M, Izumi S, Ron E, Kuramoto A, Kamada N, Dohy H, Matsuo T, Nonaka H, Thompson DE, Soda M, Mabuchi K: "Cancer incidence in atomic bomb survivors. Part III: Leukemia, lymphoma, and multiple myeloma, 1950-87." Radiat Res 1994;137:S68-S97.

Collaborators

DCEG Collaborators

  • Elaine Ron, PhD; Martha Linet, MD, MPH; Charles Land, PhD; Alice Sigurdson, PhD; Michele Doody, MS; Michal Freedman, PhD; Ruth Kleinerman, MPH; Peggy Tucker, MD; Michael Hauptmann, PhD

Other Scientific Collaborators

  • Dale Preston, PhD, Radiation Effects Research Foundation, Japan
  • Donald A. Pierce, PhD, Radiation Effects Research Foundation, Japan
  • Shoji Tokuoka, MD, Radiation Effects Research Foundation, Japan
  • Kazunori Kodama, MD, Radiation Effects Research Foundation, Japan
  • Shinji Yoshinaga, PhD, National Institute of Radiological Sciences, Japan
  • Per Hall, MD, Karolonska Institute, Sweden
  • Timothy Jorgensen, PhD, Georgetown University
  • Margaret Karagas, PhD, Dartmouth Medical College
  • Heather Nelson, PhD, Harvard University
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