The Double Exposure Study: The Impact of Job Strain and Marital Cohesion on Blood Pressure - Full Text View

Sponsored by:	Sunnybrook Health Sciences Centre
Information provided by:	Sunnybrook Health Sciences Centre
ClinicalTrials.gov Identifier:	NCT00133653

Purpose

Psychosocial and lifestyle stressors, such as job strain (JS) and marital factors have previously been associated with a sustained increase in blood pressure (BP).

In a one-year longitudinal follow-up to the Baseline Double Exposure cohort study, we, the researchers at Sunnybrook and Women's College Health Sciences Centre, evaluated whether JS and marital cohesion continued to be associated with ambulatory blood pressure (ABP) in subjects enrolled with normal or untreated high BP.

Condition	Intervention
Hypertension	Behavioral: Observational

MedlinePlus related topics: High Blood Pressure

U.S. FDA Resources

Study Type:	Observational
Study Design:	Psychosocial, Longitudinal, Defined Population, Prospective Study
Official Title:	The Impact of Job Strain and Marital Cohesion on Ambulatory Blood Pressure Over One Year: The Double Exposure Study

Further study details as provided by Sunnybrook Health Sciences Centre:

Estimated Enrollment:	250
Study Start Date:	August 2001
Estimated Study Completion Date:	July 2004

Detailed Description:

Psychosocial and lifestyle stressors, such as job strain (JS) and marital factors have previously been associated with a sustained increase in blood pressure (BP).

In a one-year longitudinal follow-up to the Baseline Double Exposure cohort study, we evaluated whether JS and marital cohesion continued to be associated with ambulatory blood pressure (ABP) in subjects enrolled with normal or untreated high BP.

Eligibility

Ages Eligible for Study:	40 Years to 65 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Age 40-65
Unmedicated for at least 6 months
Living with spouse for at least 6 months
Working for at least 6 months

Exclusion Criteria:

Working rotating or evening shifts

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00133653

Locations

Canada, Ontario
Sunnybrook & Women's College Health Sciences Centre
Toronto, Ontario, Canada, M4N 3M5

Sponsors and Collaborators

Sunnybrook Health Sciences Centre

Investigators

Principal Investigator:

Sheldon W Tobe, MD

Sunnybrook & Women's College Health Sciences Centre

More Information

Publications of Results:

Baker B, Paquette M, Szalai JP, Driver H, Perger T, Helmers K, O'Kelly B, Tobe S. The influence of marital adjustment on 3-year left ventricular mass and ambulatory blood pressure in mild hypertension. Arch Intern Med. 2000 Dec 11-25;160(22):3453-8.

Study ID Numbers:	DE-2001
Study First Received:	August 22, 2005
Last Updated:	October 28, 2005
ClinicalTrials.gov Identifier:	NCT00133653
Health Authority:	Canada: Health Canada

Keywords provided by Sunnybrook Health Sciences Centre:

Hypertension; Job Strain; Marital Strain; Blood Pressure

Study placed in the following topic categories:

Vascular Diseases
Hypertension

Additional relevant MeSH terms:

Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 14, 2009