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Sponsored by: |
Department of Veterans Affairs |
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Information provided by: | Department of Veterans Affairs |
ClinicalTrials.gov Identifier: | NCT00018642 |
The purpose of this research study is to determine whether a new drug for schizophrenia is better for the maintenance treatment than a standard drugs currently prescribed. The new medication is called quetiapine and it will be compared with a standard medication called haloperidol decanoate. The study will determine if quetiapine causes fewer problems than haloperidol with side effects such as stiffness and restlessness and whether it costs the VA more or less to treat patients with quetiapine. In addition, blood samples will be collected every three months to determine if certain chemicals in the blood can influence the outcome of the subjects' illness.
Condition | Intervention |
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Schizophrenia Schizoaffective Disorder |
Drug: quetiapine Drug: haloperidol decanoate |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Uncontrolled, Parallel Assignment, Efficacy Study |
Official Title: | Predicting the Optimal Pharmacotherapy for Outpatients With Schizophrenia |
Ages Eligible for Study: | 18 Years to 60 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria
Exclusion Criteria
Study ID Numbers: | MHBS-042-96F |
Study First Received: | July 3, 2001 |
Last Updated: | June 23, 2005 |
ClinicalTrials.gov Identifier: | NCT00018642 |
Health Authority: | United States: Federal Government |
quetiapine haloperidol decanoate |
Haloperidol Schizophrenia Haloperidol decanoate Quetiapine |
Dopamine Mental Disorders Psychotic Disorders Schizophrenia and Disorders with Psychotic Features |
Neurotransmitter Agents Disease Tranquilizing Agents Molecular Mechanisms of Pharmacological Action Anti-Dyskinesia Agents Physiological Effects of Drugs Gastrointestinal Agents Psychotropic Drugs Central Nervous System Depressants Antiemetics |
Dopamine Antagonists Antipsychotic Agents Pharmacologic Actions Pathologic Processes Autonomic Agents Therapeutic Uses Dopamine Agents Peripheral Nervous System Agents Central Nervous System Agents |