Patient-Ventilator Dyssynchrony: How is the Effect of Management?

This study is currently recruiting participants.

Verified by National Cheng-Kung University Hospital, May 2008

Sponsored by:	National Cheng-Kung University Hospital
Information provided by:	National Cheng-Kung University Hospital
ClinicalTrials.gov Identifier:	NCT00683072

Purpose

Although patient-ventilator asynchrony is a frequent phenomenon, its course following management is unknown. As the aid of a data recording system, we try to observe the consequence of patient-ventilator asynchrony following management. Our target is aimed at the patients with high asynchronization index ( > 10%) as this group of patients have been shown to have prolonged course in intensive care unit and are also prone to be tracheostomized

Condition
Respiratory Failure

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case-Only, Prospective
Official Title:	Patient-Ventilator Dyssynchrony: How is the Effect of Management?

Further study details as provided by National Cheng-Kung University Hospital:

Primary Outcome Measures:

Asynchrony index (AI). (Number of asynchrony events/total respiratory rate) [ Time Frame: 20 minutes after alternation of ventilator settings or any therapeutic means ] [ Designated as safety issue: No ]

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	40
Study Start Date:	March 2008
Estimated Study Completion Date:	December 2008
Estimated Primary Completion Date:	December 2008 (Final data collection date for primary outcome measure)

Groups/Cohorts
1

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

Between March 2008 through December 2008, patients admitted to our respiratory intensive care unit for the management of acute respiratory failure were daily screened for the presence of patient-ventilator asynchrony.

Criteria

Inclusion Criteria:

patients admitted to respiratory intensive care unit with acute respiratory failure and presence of patient-ventilator asynchrony(AI of more than 10%)
patient can trigger the ventilator

Exclusion Criteria:

High oxygen fraction: > 60%.
High PEEP need: > 12cmH2O.
Hemodynamic unstable: shock
Central nervous system problem.
Hyperacitve delirium
Without informed consent

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00683072

Contacts

Contact: Kuang Ming Liao, MD	886-6-235-3535 ext 2588	abc8870@yahoo.com.tw
Contact: Chang Wen Chen, MD, MS	886-6-235-3535 ext 2577	cwchen@mail.ncku.edu.tw

Locations

Taiwan
National Cheng-Kung University Hospital	Recruiting
Tainan, Taiwan, 704
Contact: Kuang Ming Liao, MD 886-6-235-3535 ext 2588 abc8870@yahoo.com.tw

Sponsors and Collaborators

National Cheng-Kung University Hospital

Investigators

Study Director:

Chang wen Chen, MD, MS

National Cheng-Kung University Hospital

More Information

Study ID Numbers:	NCKUH-9703023
Study First Received:	May 21, 2008
Last Updated:	May 22, 2008
ClinicalTrials.gov Identifier:	NCT00683072
Health Authority:	Taiwan: Department of Health

Keywords provided by National Cheng-Kung University Hospital:

Ventilator
patient-ventilator asynchrony

Study placed in the following topic categories:

Respiratory Insufficiency
Respiratory Tract Diseases
Respiration Disorders

ClinicalTrials.gov processed this record on January 16, 2009