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The Effect of Exercise on Muscle, Function and Cost in VA Nursing Home Residents
This study has been completed.
Sponsored by: Department of Veterans Affairs
Information provided by: Department of Veterans Affairs
ClinicalTrials.gov Identifier: NCT00105807
  Purpose

Veterans are admitted to Veterans Health Administration (VA) Nursing Homes (NH) because impairment in their ability to perform activities of daily living (ADL) overwhelms their support system (family/friends) in the community. The etiologies of this impairment are, in part, due to chronic disease, deconditioning, and immobility. Yet, after admission, NH residents frequently have decreased levels of daily activity compared with their preadmission activity. Our preliminary observations suggest that dependent, frail residents improve in function in response to exercise in a NH setting.


Condition Intervention Phase
Muscle Weakness
Behavioral: participation in low intensity exercise
Behavioral: participation in art and music activities
Phase II

Genetics Home Reference related topics: adenosine monophosphate deaminase deficiency
MedlinePlus related topics: Exercise and Physical Fitness Nursing Homes
U.S. FDA Resources
Study Type: Interventional
Study Design: Treatment
Official Title: The Effect of Exercise on Muscle, Function and Cost in VA Nursing Home Residents

Further study details as provided by Department of Veterans Affairs:

Estimated Enrollment: 120
Study Start Date: July 2002
Study Completion Date: April 2006
Arms Assigned Interventions
1 Behavioral: participation in low intensity exercise Behavioral: participation in art and music activities

Detailed Description:

Background:

Veterans are admitted to Veterans Health Administration (VA) Nursing Homes (NH) because impairment in their ability to perform activities of daily living (ADL) overwhelms their support system (family/friends) in the community. The etiologies of this impairment are, in part, due to chronic disease, deconditioning, and immobility. Yet, after admission, NH residents frequently have decreased levels of daily activity compared with their preadmission activity. Our preliminary observations suggest that dependent, frail residents improve in function in response to exercise in a NH setting.

Objectives:

By comparing an exercise group with a non-exercise group that receives a comparable level of staff attention and positive reinforcement, we will determine whether changes in function normally associated with low intensity exercise are due to exercise or to other factors.

Methods:

We conducted a blinded, prospective, randomized, controlled, clinical investigation at a VA nursing home, comparing the effect of four months of low intensity exercise with the effect of music and art activity on: 1) muscle mass, assessed by DEXA scan; 2) physical function, assessed by timed performance tests, strength and independence in ADL; and 3) the cost of NH care, assessed by measuring the cost of providing care within the NH minus the cost of providing the intervention. Study setting is a VA nursing home, resident participants are new admissions to the NH and are 65 years or older. All participants must be able to follow a one step command and be able to participate in group activity. Participants with a Mini Mental Status Exam (MMSE) of less than 24/30 must have consent of authorized representative. Screening of candidates is completed on all NH admissions. Upon completion of the consent process, participants are randomly assigned to either the exercise group or the music/art group. Baseline tests including the DEXA scan, timed performance tests and observation of ADL is completed prior to participation in activity. At the conclusion of four months of activity, all baseline tests are repeated.

Status:

Recruitment and intervention stage of this project has been completed. In order to achieve our desired number of participants, a request was made and approval received for an extension of recruitment stage from March 2005 until December 2005. Interventions would continue through March 2006 and analysis of data completed in December 2006.

  Eligibility

Ages Eligible for Study:   65 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

must be able to follow a one step command and be able to participate in group activity Participants with a Mini Mental Status Exam (MMSE) of less than 24/30 must have consent of authorized representative. Nursing Home resident

Exclusion Criteria:

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00105807

Locations
United States, Maryland
VA Maryland Health Care System, Baltimore
Baltimore, Maryland, United States, 21201
Sponsors and Collaborators
Investigators
Principal Investigator: Mary M. Grant, BSN MA VA Maryland Health Care System, Baltimore
  More Information

Responsible Party: Department of Veterans Affairs ( Grant, Mary - Principal Investigator )
Study ID Numbers: NRI 99-344
Study First Received: March 16, 2005
Last Updated: April 23, 2008
ClinicalTrials.gov Identifier: NCT00105807  
Health Authority: United States: Federal Government

Study placed in the following topic categories:
Signs and Symptoms
Muscular Diseases
Musculoskeletal Diseases
Asthenia
Neurologic Manifestations
Muscle Weakness

Additional relevant MeSH terms:
Neuromuscular Manifestations
Pathologic Processes
Nervous System Diseases

ClinicalTrials.gov processed this record on January 16, 2009