Training DIR Admin

NIH Pathway to Independence (PI) Award (K99/K00)

NINDS Intramural Applications

The Pathway to Independence Award is uniquely designed to facilitate the transition of outstanding postdoctoral candidates from mentored to independent research positions. The award contains two components, a mentored (K99) phase of at least 1 year but can last up to 2 years, and an independent (R00) phase which will have a duration of 3 years. The objective of the program is to facilitate research independence earlier in an investigator's career. Investigators complete supervised research and apply for an independent research position (tenure track or equivalent) during the mentored phase of the award. Activation of the independent award phase is contingent upon the investigator securing an independent research position. Award recipients are expected to obtain R01 support during the independent phase of the award.

Salary and Research Costs: For mentored candidates in an extramural institution, NINDS will provide up to $50,000 per year for salary support (up to $85,000 per year for applicants with a M.D. degree), and up to $20,000 for research support costs. Budget details for mentored candidates in the NIH Intramural program will be negotiated with the sponsoring laboratory and will be consistent with offers to scientists in comparable positions.

Eligibility: Eligible candidates will have less than 4 years of postdoctoral experience (whether at the NIH or elsewhere before coming to the NIH) at the time of application and currently be in one of the following types of appointments: IRTA, CRTA, VF (within VISA restrictions), or Research or Clinical Fellow in an FTE position.

Candidate Selection: Applications are submitted through the Center for Scientific Review (CSR) and reviewed by an NINDS study section. The study section will be responsible for evaluating all applications and making recommendations to the Scientific Director.

Prior approval by Scientific Director required to write an application: A postdoctoral fellow interested in applying for a K99 in an NINDS Intramural lab must obtain approval from the Scientific Director before writing the application. The request must be made by email through the current or proposed NINDS PI mentor and include the applicant’s CV, an abstract of the proposed work and a rationale for why the laboratory is suited to the mentored phase of the work. The request should be sent to Dr. Alan Koretsky with a copy to Peggy Rollins

Pre-submission review: One month prior to the CSR receipt date an advance copy of the application which has been approved by the PI mentor must be submitted to the Scientific Director for pre-submission review along with suggestions of two NINDS Intramural PIs who are suitable to perform the review. For new standing receipt dates, starting in January, 2007 - see: http://grants.nih.gov/grants/guide/notice-files/NOT-OD-07-001.html. Send the advance copy to Alan Koretsky, Ph.D. with a copy to Peggy Rollins

Official submission: Refer to PA-06-133 and receipt dates at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-07-001.html.