Search of: "Oxymetazoline" - List Results

Rank

Status

Study

Not yet recruiting

Evaluation of Ketotifen/Naphazoline Ophthalmic Solution in the Conjunctival Allergen Challenge(CAC) Model of Acute Allergic Conjunctivitis.

Condition:

Allergic Conjunctivitis

Interventions:

Drug: Ketotifen/naphazoline; Drug: Ketotifen/naphazoline and Vehicle; Drug: Ketotifen/naphazoline and Naphazoline; Drug: Ketotifen/naphazoline and Ketotifen; Drug: Ketotifen and Ketotifen/naphazoline; Drug: Ketotifen and Vehicle; Drug: Ketotifen and Naphazoline; Drug: Ketotifen; Drug: Naphazoline and Ketotifen/naphazoline; Drug: Naphazoline and Vehicle; Drug: Naphazoline; Drug: Naphazoline and Ketotifen; Drug: Vehicle and Ketotifen/naphazoline; Drug: Vehicle; Drug: Vehicle and Naphazoline; Drug: Vehicle and Ketotifen

Recruiting

Evaluation of a Ketotifen/Naphazoline Ophthalmic Solution in the Conjunctival Allergen Challenge (CAC) Model of Acute Allergic Conjunctivitis.

Condition:

Allergic Conjunctivitis

Interventions:

Drug: Ketotifen/naphazoline; Drug: Ketotifen/naphazoline & Vehicle; Drug: Ketotifen/naphazoline and Naphazoline; Drug: Ketotifen/naphazoline and Ketotifen; Drug: Ketotifen and Ketotifen/naphazoline; Drug: Ketotifen and vehicle; Drug: Ketotifen and Naphazoline; Drug: Ketotifen; Drug: Naphazoline and Ketotifen/naphazoline; Drug: Naphazoline and Vehicle; Drug: Naphazoline; Drug: Naphazoline and Ketotifen; Drug: Vehicle and Ketotifen/naphazoline; Drug: Vehicle; Drug: Vehicle and Naphazoline; Drug: Vehicle and Ketotifen

Completed

Study of Mometasone Furoate Nasal Spray and Oxymetazoline Nasal Spray Given Together Once A Day To Treat Seasonal Allergic Rhinitis (P04500)(COMPLETED)

Condition:	Seasonal Allergic Rhinitis
Interventions:	Drug: OXY combination: mometasone furoate nasal spray (MFNS) and oxymetazoline nasal spray (OXY); Drug: OXY combination: mometasone furoate nasal spray (MFNS) and oxymetazoline nasal spray (OXY); Drug: mometasone furoate nasal spray (MFNS) once daily; Drug: oxymetazoline nasal spray (OXY) twice daily; Drug: Placebo

Completed

A Study of the Safety and Efficacy of Combination Therapy With Morphine, Phenylephrine and Sorbitol in Human Subjects

Condition:	Acute Pain
Interventions:	Drug: Morphine; Drug: Morphine; Drug: Sorbitol+Phenylephrine; Drug: Sorbitol+Phenylephrine+Morphine; Drug: Sorbitol low concentration+Phenylephrine+Morphine

Recruiting

Oxymetazoline Hydrochloride in Combination With Nasal Glucocorticosteroid for Perennial Allergic and Non-Allergic Rhinitis in Subjects With Persistent Nasal Congestion

Condition:	Chronic Rhinitis
Intervention:	Drug: Oxymetazoline Hydrochloride

Completed

Phenylephrine Pediatric Pharmacokinetic Study

Condition:	Rhinitis
Intervention:	Drug: phenylephrine HCl

Completed

Phenylephrine in Septic Shock

Condition:	Septic Shock
Interventions:	Drug: Phenylephrine; Drug: Norepinephrine

Recruiting

Phenylephrine in Spinal Anesthesia in Preeclamptic Patients

Conditions:	Preeclampsia; Spinal Anesthesia; Hypotension; Cesarean Section
Interventions:	Drug: Ephedrine; Drug: Phenylephrine

Recruiting

Treatment of Acute Sinusitis

Conditions:	Acute Respiratory Infections; Acute Rhinosinusitis
Interventions:	Drug: Acetaminophen; Drug: Amoxicillin; Drug: Dextromethorphan hydrobromide (10mg/5ml) with guaifenesin (100mg/5ml); Drug: Mucinex OTC (guaifenesin); Drug: Pseudoephedrine Sustained Action; Drug: Saline spray (0.65%)

Recruiting

A Combination of Intranasal Steroid/Oxymetazoline Leads to Faster Relief of Nasal Congestion Without Inducing Rhinitis Medicamentosa

Condition:	Allergic Rhinitis
Intervention:	Drug: fluticasone furoate and/or oxymetazoline or placebo

Completed

Phenylephrine Versus Norepinephrine in Septic Shock

Condition:	Septic Shock
Intervention:	Drug: Phenylephrine

Completed

Ideal Dose of Phenylephrine to Treat Low Blood Pressure During Cesarean Section

Conditions:	Hypotension; Nausea
Intervention:	Drug: phenylephrine

Completed

2.5% and 10% Phenylephrine for Mydriasis in Diabetic Patients With Darkly Pigmented Irides

Condition:	Diabetes Mellitus
Intervention:	Drug: 2.5% or 10% phenylephrine

Terminated

A Study to Evaluate Topical Phenylephrine Gel in the Management of Faecal Incontinence

Condition:	Faecal Incontinence
Intervention:	Drug: 10% Phenylephrine hydrochloride gel

Completed

Phase 4 Study - Mucinex D as Adjunct Therapy

Conditions:	Acute Respiratory Infection; Bronchitis; Rhinosinusitis
Intervention:	Drug: Mucinex D (600 mg guaifenesin and 60 mg pseudoephedrine HCl extended-release bi-layer tablets)

Completed

Single Dose of 1% Tropicamide and 10% Phenylephrine for Pupillary Dilation

Condition:	Eye Diseases
Intervention:	Drug: 1% tropicamide and 10% phenylephrine

Recruiting

Phenylephrine for Spinal Induced Hypotension

Condition:	Hypotension
Intervention:	Drug: Phenylephrine bolus

Completed

The Effects of Phenylephrine Compared With Those of Placebo and Pseudoephedrine on Nasal Congestion in Subjects With Seasonal Allergic Rhinitis (SAR) (Study P04579)(COMPLETED)

Condition:	Rhinitis, Allergic, Seasonal
Intervention:	Drug: phenylephrine, pseudoephedrine

Not yet recruiting

Differential Adrenoreceptor Mediated Tachyphylaxis and Upregulation

Conditions:	Allergic Rhinitis; Tachyphylaxis; Rhinitis Medicamentosa
Interventions:	Drug: Oxymetazoline 0.05% w/v; Drug: Budesonide aqueous nasal spray 64 micrograms; Drug: Prazosin 1 mg tablet; Drug: Placebo tablet to Prazosin

Recruiting

Hemodynamics and Extravascular Lung Water in Acute Lung Injury

Condition:

Acute Lung Injury

Interventions:

Drug: Diuresis (furosemide) part I; Other: Fluid Bolus (crystalloid or albumin); Other: Fluid Bolus (crystalloid or albumin); Drug: Vasopressors (Norepinephrine, Vasopressin, Phenylephrine, Epinephrine); Drug: Vasopressors (Norepinephrine, Vasopressin, Phenylephrine, Epinephrine); Drug: Dobutamine; Drug: Dobutamine; Other: Concentrate all drips and nutrition; Drug: Diuresis (furosemide) part II; Procedure: Dialysis