NIGMS - Results http://www.nigms.nih.gov/News/Results/ NIH CMS RSS feeder 2.0 Two Classes of Chemicals Disrupt Pathway Involved in Diseases http://www.nigms.nih.gov/News/Results/013009a.htm Fri, 30 Jan 2009 13:47:53 EST {2364B722-2D9C-48E5-A96D-903BE5FA4FF2} An NIGMS-supported chemical library screen identified two new classes of compounds that affect a biochemical system involved in cancer and many diseases. Many Genetic Variations Linked to Leukemia Treatment http://www.nigms.nih.gov/News/Results/012709b.htm Fri, 30 Jan 2009 13:46:06 EST {8162E9BA-45E2-4EA6-AE2D-366E08F2314A} Scientists in the NIGMS-funded Pharmacogenetics Research Network have linked scores of genetic variations with how children respond to leukemia drugs. Study Links Oncogene and Tumor Suppressor http://www.nigms.nih.gov/News/Results/012909.htm Fri, 30 Jan 2009 11:51:37 EST {3444B7CC-1371-4BAD-939F-C730E8132D72} NIGMS-funded researchers have found a connection between two signaling pathways associated with cancer. How the Protein Alphabet Can Evolve http://www.nigms.nih.gov/News/Results/012709.htm Fri, 30 Jan 2009 11:50:00 EST {D846FF5F-9721-437A-9A2C-39014AB5FB39} NIGMS-funded researchers have demonstrated how a rare and relatively new amino acid was incorporated into the menu for protein synthesis. How Editing Error Leads to a Neurodegenerative Disease http://www.nigms.nih.gov/News/Results/012809a.htm Thu, 29 Jan 2009 16:56:08 EST {96C8755C-74B6-4949-8395-598DCE7F1C27} NIGMS-funded molecular biologists have explained how a gene mutation causes atypical RNA splicing that results in a devastating disease. Unzipping Molecules to Understand DNA Packing http://www.nigms.nih.gov/News/Results/012809b.htm Thu, 29 Jan 2009 16:54:37 EST {FC918604-9809-4CC8-B581-24A422D99AAE} NIGMS-funded researchers used an optical trap to unwrap strands of DNA from their histone cores to understand this important interaction. Stem-Cell Like Properties in Plant Cells http://www.nigms.nih.gov/News/Results/012809c.htm Thu, 29 Jan 2009 16:52:59 EST {8560E51D-1383-4851-9393-04DB880B03CD} NIGMS-funded biologists have discovered that ordinary plants cells have the ability to replace lost organs in plants. Fluorescent Proteins Tag Structures in Living Cells http://www.nigms.nih.gov/News/Results/012509.htm Thu, 29 Jan 2009 16:49:37 EST {8A6862B4-7317-42B5-AC4C-C3C66E4EA727} NIGMS-funded researchers are developing advanced fluorescent probes to watch structures and processes in living cells. Gatekeepers to the Nucleus Implicated in Aging http://www.nigms.nih.gov/News/Results/012209.htm Thu, 29 Jan 2009 16:48:48 EST {E7D2747A-1BDC-42A0-B944-8B2397372DB7} NIGMS-funded researchers have discovered that cells do not replace or repair the core structure of nuclear pores, which become leaky over time. Adaptation Drives Human Evolution http://www.nigms.nih.gov/News/Results/011609.htm Thu, 29 Jan 2009 16:48:01 EST {1C79CA1E-E085-4AE0-B78D-CDB014D1F7AF} An NIGMS-funded study shows that adaptation, rather than neutral change, plays a large role in human evolution. Cooperating Proteins Could Be Cancer Drug Targets http://www.nigms.nih.gov/News/Results/011609b.htm Wed, 28 Jan 2009 17:57:00 EST {84FBFC34-9926-4C87-AB23-835DED9627BA} NIGMS-funded biochemists have found two proteins that work together to ensure proper chromosome segregation during cell division.