Method for Analysis of Biomarkers Concentrated with Biomarker Attractants
Description of Invention:
Biological fluids are the repositories of vast number of molecules that are excreted or otherwise shed by cells. These molecules present in biological fluids reflect the physiological and pathological states of the cells that are in contact by the fluids or the cells from which these molecules are derived. A major goal of clinical diagnostics is to correlate the particular molecules (biomarkers) present in biological fluids with particular disease states.
The present invention relates to analysis of molecules present in biological fluids. Specifically, it discloses a diagnostic method for isolating/analyzing biomarker attractant molecules for the presence of bound fragments of cellular proteins that are known to correlate with particular biological states in specific anatomic or physiologic locations.
Inventors:
Arpita Mehta et al. (NCI)
Patent Status:
DHHS Reference No. E-167-2003/0 --
U.S. Provisional Application No. 60/509,782 filed 08 Oct 2003
PCT Application No. PCT/US2004/33305 filed 08 Oct 2004, which published as WO 2005/036180 on 21 Apr 2005
For Additional Information Please Contact: Fatima Sayyid M.H.P.M.
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: (301) 435-4521
Email: sayyidf@mail.nih.gov
Fax: (301) 402-0220
