Chromatographic Method And Device For Preparing Blood Serum For Compatibility Testing
Description of Invention:
The present invention provides a new method for antiglobulin testing of serum from a potential blood transfusion recipient. This process and device removes warm antibodies from serum to allow for the identification of alloantibodies present in the sample. The multiple absorptions required by current methods to remove the warm antibodies from serum of a potential blood transfusion recipient is superseded by this invention. The disclosed invention will remove the majority of warm antibodies in a single one-hour absorption. This invention also eliminates the need for pretreatment of cells with expensive reagents. Use of this column and method does not remove any clinically significant alloantibodies. Therefore, transfusion history accuracy and subsequent risk to the patient is greatly reduced.
Inventors:
R Butz (CC)
Patent Status:
DHHS Reference No. E-141-94/0 filed 18 Oct 1995
Serial No. 08/789,096 filed 11 Oct 1996 U.S. Patent 6,017,721 issued 25 Jan 2000
For Additional Information Please Contact: Michael Shmilovich J.D.
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: (301) 435-5019
Email: shmilovm@mail.nih.gov
Fax: (301) 402-0220
