Description of Invention:
Available for licensing and commercial development are nanoparticle compositions comprising a phospholipid or diphosphatidyl glycerol component, an optional linker and a multifunctional ligand. A patent application has been filed covering the nanoparticle compositions and their methods of use as site-specific imaging or therapeutic agents. The particles are preferably single lipid compounds or single lipid nanoparticles (SLNs) prepared from single lipids (e.g., being a lipid molecule of a single lipid type or of a uniform structural type). Four exemplary SLNs might be the following:
Example I
Example II
Example III
Example IV
Inventors:
S. Narasimhan Danthi (CC) King Li (CC) Jianwu Xie (CC)
Patent Status:
DHHS Reference No. E-100-2004/0 --
U.S. Provisional Application No. 60/645,142 filed 19 Jan 2005 Licensing Status: This technology is no longer available for licensing.
Portfolios: Devices/Instrumentation
Devices/Instrumentation-Diagnostics-Imaging Devices/Instrumentation-Research Materials-Biologicals and Chemicals Devices/Instrumentation-Diagnostics Devices/Instrumentation-Research Materials
For Additional Information Please Contact: Michael Shmilovich J.D.
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: (301) 435-5019
Email: shmilovm@mail.nih.gov
Fax: (301) 402-0220
