Laboratory of Cardiovascular Science Intramural Program Investigators ^
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Mark Talan, M.D., Ph.D., Senior Investigator
Chief, Translational Cardiovascular Studies Section
Mark Talan, M.D., Ph.D.Dr. Talan was trained as a physician at the First Leningrad Medical School in Russia. He received his Ph.D. in Physiology at the Pavlov Institute of Physiology in Russia where he continued to work as a principal researcher before coming to the NIA in 1980. His studies at the NIA in the area of thermoregulation, regulation of hemodynamics, and operant conditioning of autonomic functions evolved into his present interests of development and assessment of genetic therapeutic interventions in cardiovascular pathology using different experimental models.

Research Interests: The broad objective of this program is to perform preclinical experimentation on animal models of myocardial and hindlimb ischemia as well as on different experimental models of heart failure to evaluate the therapeutic potential of gene therapy with angiogenic growth factors. In vivo experiments are aimed at characterizing clinically relevant animal models and optimal conditions, vectors, and routes of delivery at which gene transfer of angiogenic growth factors induce therapeutic angiogenesis.

Contact Information:
Laboratory of Cardiovascular Science
Gerontology Research Center
5600 Nathan Shock Drive
Baltimore, MD 21224-6825

Phone 410-558-8214
Fax 410-558-8150
E mail talanm@grc.nia.nih.gov

For more information about the Laboratory:
http://www.grc.nia.nih.gov/branches/lcs/lcs.htm

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Updated: Friday May 16, 2008