| Laboratory of Neurosciences |
Intramural Program Investigators ^ Home ^ |
| Mark P. Mattson, Ph.D., Senior Investigator Chief, Laboratory of Neurosciences and Chief, Cellular and Molecular Neurosciences Section |
 Dr. Mattson received his Ph.D. in Biology from the University of Iowa in 1986. After 3 years of postdoctoral studies in Developmental Neuroscience at Colorado State University, Dr. Mattson took a faculty position at the Sanders-Brown Research Center on Aging at the University of Kentucky Medical Center where he was promoted to Full Professor in 1997. Dr. Mattson is currently Chief of the Laboratory of Neurosciences at the National Institute on Aging, and Professor of Neuroscience at Johns Hopkins University. He is Editor-in-Chief of the Journal of Molecular Neuroscience, and a Managing or Associate Editor of the Journal of Neuroscience, Journal of Neurochemistry and Journal of Neuroscience Research. In addition, he has edited 7 volumes in the areas of mechanisms of cell death, aging and age-related neurodegenerative disorders. Dr. Mattson has received numerous awards including the Metropolitan Life Foundation Award and the Alzheimer's Association Zenith Award. He is considered a leader in the area of cellular and molecular mechanisms underlying neuronal plasticity and neurodegenerative disorders, and has made major contributions to understanding of the pathogenesis of Alzheimer's disease, and to its prevention and treatment. Dr. Mattson has published more than 300 original research articles and more than 80 review articles. |
| Research Interests: The Cellular and Molecular Neurosciences Section (CMNS) employs a multifaceted array of experimental models of aging and age-related neurodegenerative disorders in order to establish the molecular and biochemical changes that occur during aging and in disorders such as Alzheimer's, Parkinson's and Huntington's diseases and stroke. Data obtained in these experimental models are integrated with data obtained in studies of both normal elderly humans and patients with neurodegenerative disorders to arrive at conclusions as to why neuronal dysfunction and degeneration occur in the disorders. In addition to identifying the molecular and cellular alterations that lead to neuronal degeneration in age-related neurological disorders, investigators are elucidating the cellular signaling mechanisms that allow successful brain aging. |
| Contact Information: Laboratory of Neurosciences Biomedical Research Center, 05C214 251 Bayview Boulevard, Suite 100 Baltimore, MD 21224-6825 Phone 410-558-8463 Fax 410-558-8465 E mail mattsonm@grc.nia.nih.gov For more information about the Laboratory: http://www.grc.nia.nih.gov/branches/lns/mcnu.htm |
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