Section on Biomedical Stochastic Physics

Head: Amir H. Gandjbakhche

We devise quantitative theories, develop methodologies, and design instrumentation to study biological phenomena that are characterized by elements of randomness in both space and time. In developing quantitative theories applicable to quantitative optical spectroscopy and tomographic imaging of tissues, we analyze different optical sources of contrast such as endogenous or exogenous fluorescent labels, absorption (e.g., hemoglobin or chromophore concentration), and/or scattering. We design and conduct experiments and computer simulations to validate our theoretical findings. In collaboration with other scientists at the NIH and researchers around the country and world, we investigate physiological sites for which optical techniques might be clinically practical while yielding new diagnostic knowledge and/or generating less morbidity than existing diagnostic methods. Given that angiogenesis plays an essential role in establishing tumor malignancy, we try to establish quantitative methods and in vitro assays to study the mechanisms underlying angiogenesis through stochastic modeling.

Resources

• Employee Listing
• E-Mail the Lab: amir@helix.nih.gov
• SBSP Home Page