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Compounds In Testing

Each material is given in the diet at the following levels (part per million (PPM) by weight).

 

Cohort 1:

Compound

Concentration in food

Age at treatment initiation

Aspirin

20 ppm

4 months

NFP

200 ppm

4 months

NDGA

2,500 ppm

9 months

4-OH-PBN

315 ppm

4 months

 

Cohort 2:

Compound

Concentration in food

Age at treatment initiation

CAPE

30 ppm

4 months

CAPE

300 ppm

4 months

Enalapril Maleate

120 ppm

4 months<

Rapamycin

14 ppm

20 month

 

Cohort 3:

Compound

Concentration in food

Age at treatment initiation

Rapamycin

14 ppm

9 months

Simvastatin

12 ppm

10 months

Simvastatin

120 ppm

10 months

Resveratrol

300 ppm

12 months

Resveratrol

1200 ppm

12 months

 
Cohort 4:

Compound

Concentration in food

Age at treatment initiation

Resveratrol

300 ppm

4 months

N-acetyl-cysteine

5000 ppm

10 months

Oxaloacetic acid

2200 ppm

4 months

Green tea extract

2000 ppm

4 months

Curcumin

2000 ppm

4 months

Medium Chain Triglyceride Oil

60000 ppm

4 months

 


Page last updated Sep 26, 2008