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Link to the citations for PA-09-061 - Vulnerable Dendrites and Synapses in Aging and Alzheimer’s Disease (R01)

Link for PA-09-061

Citations:

Almeida CG, Takahashi RH, Gouras GK. J Neurosci. 2006 Apr 19;26 (16):4277-88. Beta-amyloid accumulation impairs multivesicular body sorting by inhibiting the ubiquitin-proteasome system. PMID: 16624948.

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Chin J, Palop JJ, Yu GQ, Kojima N, Masliah E, Mucke L. J Neurosci. 2004 May 12;24(19):4692-7. Fyn kinase modulates synaptotoxicity, but not aberrant sprouting, in human amyloid precursor protein transgenic mice. PMID: 15140940.

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Jiang Q, Lee CY, Mandrekar S, Wilkinson B, Cramer P, Zelcer N, Mann K, Lamb B, Willson TM, Collins JL, Richardson JC, Smith JD, Comery TA, Riddell D, Holtzman DM, Tontonoz P, Landreth GE. Neuron. 2008 Jun 12;58(5):681-93. ApoE promotes the proteolytic degradation of Abeta. PMID: 18549781.

Lacor PN, Buniel MC, Chang L, Fernandez SJ, Gong Y, Viola KL, Lambert MP, Velasco PT, Bigio EH, Finch CE, Krafft GA, Klein WL. J Neurosci. 2004 Nov 10;24(45):10191-200. Synaptic targeting by Alzheimer's-related amyloid beta oligomers. PMID: 15537891.

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Mocanu MM, Nissen A, Eckermann K, Khlistunova I, Biernat J, Drexler D, Petrova O, Schönig K, Bujard H, Mandelkow E, Zhou L, Rune G, Mandelkow EM. J Neurosci. 2008 Jan 16;28(3):737-48. The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy. PMID: 18199773.

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Oakley H, Cole SL, Logan S, Maus E, Shao P, Craft J, Guillozet-Bongaarts A, Ohno M, Disterhoft J, Van Eldik L, Berry R, Vassar R. Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation. J Neurosci. 2006 Oct 4;26(40):10129-40. PMID: 17021169.

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Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ. Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med. 2008 Aug;14(8):837-42. Epub 2008 Jun 22. PMID: 18568035.

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Zhao L, Ma QL, Calon F, Harris-White ME, Yang F, Lim GP, Morihara T, Ubeda OJ, Ambegaokar S, Hansen JE, Weisbart RH, Teter B, Frautschy SA, Cole GM.  Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease. Nat Neurosci. 2006 Feb;9(2):234-42. Epub 2006 Jan 15. PMID: 16415866.


Page last updated Jan 13, 2009