Richard W Childs's Web Page

(Last updated by Richard Childs on 3/18/2008 at 8:33 AM.)

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Publications

1 Takahashi Y, Harashima N, Kajigaya S, Yokoyama H, Cherkasova E, McCoy JP, Hanada KI, Mena O, Kurlander R, Abdul T, Srinivasan R, Lundqvist A, Malinzak E, Geller N, Lerman MI, Childs R
Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells.
J Clin Invest 118(3): 1099-1109, 2008. [Text Abstract on PubMed]
2 Sandmaier BM, Mackinnon S, Childs RW.
Reduced intensity conditioning for allogeneic hematopoietic cell transplantation: current perspectives.
Biol Blood Marrow Transplant 13 Suppl 1: 87-97, 2007. [Text Abstract on PubMed]
3 Savani BN, Mielke S, Adams S, Uribe M, Rezvani K, Yong AS, Zeilah J, Kurlander R, Srinivasan R, Childs R, Hensel N, Barrett A
Rapid natural killer cell recovery determines outcome after T-cell-depleted HLA-identical stem cell transplantation in patients with myeloid leukemias but not with acute lymphoblastic leukemia.
Leukemia 21(10): 2145-52, 2007. [Text Abstract on PubMed]
4 Solomou EE, Gibellini F, Stewart B, Malide D, Berg M, Visconte V, Green S, Childs R, Chanock SJ, Young N
Perforin gene mutations in patients with acquired aplastic anemia.
Blood 109(12): 5234-7, 2007. [Text Abstract on PubMed]
5 Yao YG, Childs RW, Kajigaya S, McCoy JP, Young N
Mitochondrial DNA sequence heterogeneity of single CD34+ cells after nonmyeloablative allogeneic stem cell transplantation.
Stem Cells 25(10): 2670-6, 2007. [Text Abstract on PubMed]
6 Lundqvist A, Abrams SI, Schrump DS, Alvarez G, Suffredini D, Berg M, Childs R.
Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity.
Cancer Res 66(14): 7317-25, 2006. [Text Abstract on PubMed]
7 Lundqvist A, McCoy JP, Samsel L, Childs R.
Reduction of GVHD and enhanced anti-tumor effects after adoptive infusion of alloreactive Ly49-mismatched NK-cells from MHC-matched donors.
Blood: 2006. [Text Abstract on PubMed]
8 Srinivasan R, Daniels J, Fusaro V, Lundqvist A, Killian JK, Geho D, Quezado M, Kleiner D, Rucker S, Espina V, Whiteley G, Liotta L, Petricoin E, Pittaluga S, Hitt B, Barrett AJ, Rosenblatt K, Childs RW.
Accurate diagnosis of acute graft-versus-host disease using serum proteomic pattern analysis.
Exp Hematol 34(6): 796-801, 2006. [Text Abstract on PubMed]
9 Srinivasan R, Takahashi Y, McCoy JP, Espinoza-Delgado I, Dorrance C, Igarashi T, Lundqvist A, Barrett AJ, Young NS, Geller N, Childs RW.
Overcoming graft rejection in heavily transfused and allo-immunised patients with bone marrow failure syndromes using fludarabine-based haematopoietic cell transplantation.
Br J Haematol 133(3): 305-14, 2006. [Text Abstract on PubMed]
10 Yang JC, Childs R.
Immunotherapy for renal cell cancer.
J Clin Oncol 24(35): 5576-83, 2006. [Text Abstract on PubMed]
11 Childs R, Srinivasan
High-dose chemotherapy and allogeneic immunotherapy.
Lancet 366(9482): 273-5, 2005. [Text Abstract on PubMed]
12 Griffith LM, McCoy JP, Bolan CD, Stroncek DF, Pickett AC, Linton GF, Lundqvist A, Srinivasan R, Leitman SF, Childs RW.
Persistence of recipient plasma cells and anti-donor isohaemagglutinins in patients with delayed donor erythropoiesis after major ABO incompatible non-myeloablative haematopoietic cell transplantation.
Br J Haematol 128(5): 668-75, 2005. [Text Abstract on PubMed]
13 Savani BN, Srinivasan R, Espinoza-Delgado I, Dorrance C, Takahashi Y, Igarashi T, Rezvani K, Lundqvist A, Barrett AJ, Childs R
Treatment of relapsed blast-phase Philadelphia-chromosome-positive leukaemia after non-myeloablative stem-cell transplantation with donor lymphocytes and imatinib.
Lancet Oncol 6(10): 809-12, 2005. [Text Abstract on PubMed]
14 Carvallo C, Geller N, Kurlander R, Srinivasan R, Mena O, Igarashi T, Griffith LM, Linehan WM, Childs RW.
Prior chemotherapy and allograft CD34+ dose impact donor engraftment following nonmyeloablative allogeneic stem cell transplantation in patients with solid tumors.
Blood 103(4): 1560-3, 2004. [Text Abstract on PubMed]
15 Childs RW, Barrett
Nonmyeloablative allogeneic immunotherapy for solid tumors.
Annu Rev Med 55: 459-75, 2004. [Text Abstract on PubMed]
16 Igarashi T, Wynberg J, Srinivasan R, Becknell B, McCoy JP, Takahashi Y, Suffredini DA, Linehan WM, Caligiuri MA, Childs RW.
Enhanced cytotoxicity of allogeneic NK cells with killer immunoglobulin-like receptor ligand incompatibility against melanoma and renal cell carcinoma cells.
Blood 104(1): 170-7, 2004. [Text Abstract on PubMed]
17 Srinivasan R, Chakrabarti S, Walsh T, Igarashi T, Takahashi Y, Kleiner D, Donohue T, Shalabi R, Carvallo C, Barrett AJ, Geller N, Childs
Improved survival in steroid-refractory acute graft versus host disease after non-myeloablative allogeneic transplantation using a daclizumab-based strategy with comprehensive infection prophylaxis.
Br J Haematol 124(6): 777-86, 2004. [Text Abstract on PubMed]
18 Takahashi Y, McCoy JP, Carvallo C, Rivera C, Igarashi T, Srinivasan R, Young NS, Childs RW.
In vitro and in vivo evidence of PNH cell sensitivity to immune attack after nonmyeloablative allogeneic hematopoietic cell transplantation.
Blood 103(4): 1383-90, 2004. [Text Abstract on PubMed]
19 Bolan CD, Leitman SF, Griffith LM, Wesley RA, Procter JL, Stroncek DF, Barrett AJ, Childs RW.
Delayed donor red cell chimerism and pure red cell aplasia following major ABO-incompatible nonmyeloablative hematopoietic stem cell transplantation.
Blood 98(6): 1687-94, 2001. [Text Abstract on PubMed]
20 Horwitz ME, Barrett AJ, Brown MR, Carter CS, Childs R, Gallin JI, Holland SM, Linton GF, Miller JA, Leitman SF, Read EJ, Malech H
Treatment of chronic granulomatous disease with nonmyeloablative conditioning and a T-cell-depleted hematopoietic allograft.
N Engl J Med 344(12): 881-8, 2001. [Text Abstract on PubMed]
21 Childs R, Chernoff A, Contentin N, Bahceci E, Schrump D, Leitman S, Read EJ, Tisdale J, Dunbar C, Linehan WM, Young NS, Barrett AJ.
Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation.
N Engl J Med 343(11): 750-8, 2000. [Text Abstract on PubMed]
22 Childs R, Clave E, Contentin N, Jayasekera D, Hensel N, Leitman S, Read EJ, Carter C, Bahceci E, Young NS, Barrett AJ.
Engraftment kinetics after nonmyeloablative allogeneic peripheral blood stem cell transplantation: full donor T-cell chimerism precedes alloimmune responses.
Blood 94(9): 3234-41, 1999. [Text Abstract on PubMed]
23 Childs RW, Clave E, Tisdale J, Plante M, Hensel N, Barrett J.
Successful treatment of metastatic renal cell carcinoma with a nonmyeloablative allogeneic peripheral-blood progenitor-cell transplant: evidence for a graft-versus-tumor effect.
J Clin Oncol 17(7): 2044-9, 1999. [Text Abstract on PubMed]