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Large Portion of Late-Stage Breast Cancers Associated With Absence of Screening
Increasing mammography screening rates and investing in research to improve
breast cancer detection technologies should be top priorities, according to
authors of a study published in the October 20 Journal of the National Cancer
Institute. As many as 92 percent of late-stage breast cancer cases in
the United States could be diagnosed and treated earlier, when there is greater
likelihood of effective treatment, if the healthcare system focused on
recruiting women who have not been recently screened, and if early detection
techniques could be improved to more accurately detect cancer. The study was
conducted by researchers at the National Cancer Institute (NCI), part of the
National Institutes of Health (NIH), and the Cancer Research Network, a
consortium of integrated health plans.Study results indicated that not
having had a screening mammogram for 1 to 3 years prior to diagnosis was
associated with 52 percent of late-stage breast cancer cases. The authors state
that to improve breast cancer outcomes, priority should be placed on reaching
unscreened women and encouraging them to have mammograms - especially older,
unmarried, less educated, and/or low income women, whom they found were less
likely to have been screened. "The good news is that there is a lot known about
how to reach women who have never been screened or who fail to get regular
mammograms," said Dr. Stephen Taplin, a senior scientist in NCI's Division of
Cancer Control and Population Sciences and lead author of the study. "The
challenge is to put this knowledge into practice." Read
more
Nutrition: A New Frontier in Cancer Research
The obesity epidemic has generated intense concern in the medical community,
and rightfully so. It has had devastating consequences for our nation's health
and health care system, driving rates of several chronic illnesses into the
stratosphere and heaping tens of billions of dollars onto an already strained
health care budget. And as we are beginning to better appreciate, obesity has
also significantly affected cancer incidence, progression, and death rates. In
fact, the most recent estimates attribute 3.2 percent of all new cancers - 14
percent of cancer deaths in men and 20 percent in women - to obesity.NCI, on
its own and in partnership with other HHS agencies, is focused on better
understanding the link between obesity and cancer and, at the same time,
working to minimize the epidemic's impact. We are also beginning to better
understand that the influence of diet on cancer goes well beyond questions of
quantity and energy expenditure. To be sure, the food we eat every day is
remarkably complex. Its nutrients and molecules have profound genetic and
cellular effects that directly influence cancer susceptibility. The components
of our daily diet - the calcium in milk, the zinc in chicken and nuts, the
flavonoids in onions and carrots, the fatty acids in tuna or avocados - all
alter a broad array of cancer-related events, including inflammatory response,
carcinogen metabolism, cell death, and DNA repair. Read
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The NCI Cancer Bulletin is produced by the National Cancer Institute
(NCI). NCI, which was established in 1937, leads the national effort to
eliminate the suffering and death due to cancer. Through basic, clinical, and
population-based biomedical research and training, NCI conducts and supports
research that will lead to a future in which we can identify the environmental
and genetic causes of cancer, prevent cancer before it starts, identify cancers
that do develop at the earliest stage, eliminate cancers through innovative
treatment interventions, and biologically control those cancers that we cannot
eliminate so they become manageable, chronic diseases.
For more information on cancer, call 1-800-4-CANCER or visit
http://www.cancer.gov.
NCI Cancer Bulletin staff can be reached at
ncicancerbulletin@mail.nih.gov.
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