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Top 20 Commercially Successful Inventions*

VACCINES AND THERAPEUTICS
Invention Description Inventor Rank
HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins Lowy et al. (NCI) (2)
Monoclonal Antibody for Treatment of Respiratory Syncytial Virus Murphy et al. (NIAID) (3)
Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 Erickson et al. (NCI) (4)
Proteosome Inhibitor for Treatment of Multiple Myeloma Gupta (NCI) (5)
AIDS Drug ddI Mitsuya et al. (NCI) (7)
Synthetic Thyrotropin as Adjuvant in Thyroid Cancer Wondisford et al. (NIDDK) (8)
Paclitaxel as a Cancer Treatment Wilson et al. (NCI) (10)
Nutritional Supplement to Treat Macular Degeneration Ferris et al. (NEI) (11)
Hepatitis A Vaccine Daemer et al. / Funkhouser et al. (NIAID) (12)
Vaccinia Virus Vector Used in Veterinary Vaccines Moss et al. (NIAID) (14)
Palifermin for Treatment of Oral Mucositis Rubin et al. (NCI) (18)
DIAGNOSTICS
Invention Description Inventor Rank
HIV-1 Diagnostic Kit Gallo et al. (NCI) / Montagnier et al. (6)
Her-2 Diagnostic for Breast Cancer King et al. (NCI) (9)
Genoyping of HIV Protease Gene Oroszlan et al. (NCI) (15)
Norwalk-like Virus Diagnostic Kit Green et al. (NIAID) (16)
HTLV-1/2 Diagnostic Kit Papas et al. (NCI) (20)
DEVICES / SOFTWARE
Invention Description Inventor Rank
Paclitaxel-Eluting Coronary Stent System Kinsella et al. (NIA) (1)
Diffusion Tensor MRI Software Basser et al. (NICHD) (13)
Software for MRI Enhancement Balaban et al. (NHLBI) (17)
RESEARCH MATERIALS
Invention Description Inventor Rank
Purified Transforming Growth Factor Beta (TGF-beta) Sporn et al. (NCI) (19)

*for FY 2008, based on royalties on product sales

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