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Top 20 Commercially Successful Inventions*

VACCINES AND THERAPEUTICS
Invention Description Inventor Rank
Monoclonal Antibody for Treatment of RSV Murphy et al. (NIAID) (2)
AIDS Drug ddI Mitsuya et al. (NCI) (4)
Paclitaxel as a Cancer Treatment Wilson et al. (NCI) (5)
Synthetic Thyrotropin as Adjuvant in Thyroid Cancer Wondisford et al. (NIDDK) (6)
Hepatitis A Vaccine (Strain HM-175) Daemer et al. / Funkhouser et al. (NIAID) (7)
Nutritional Supplement to Treat Macular Degeneration Ferris et al. (NEI) (8)
Radioimmunotherapy for Non-Hodgkin's Lymphoma Gansow (NCI) (9)
Proteosome Inhibitor for Treatment of Multiple Myeloma Gupta (NCI) (10)
AIDS Drug ddC Mitsuya et al. (NCI) (18)
DIAGNOSTICS
Invention Description Inventor Rank
Serological Detection of Antibodies to HIV-1 Gallo et al. (NCI) / Montagnier et al. (3)
DNA Probe for Breast Cancer Diagnosis King et al. (NCI) (12)
Genoyping of HIV Protease Gene Oroszlan et al. (NCI) (13)
Serological Detection of Antibodies to HTLV-1 Papas et al. (NCI) (15)
INSTRUMENTATION/DEVICES
Invention Description Inventor Rank
Paclitaxel-Eluting Coronary Stent System Kinsella et al. (NIA) (1)
Enhanced Magnetic Resonance Imaging Through Magnetization Transfer Balaban et al. (NHLBI) (11)
Laser Capture Microdissection Liotta et al. (NCI) (14)
RESEARCH MATERIALS
Invention Description Inventor Rank
Reconstituted Basement Membrane Kleinman et al. (NIDCR) (16)
Neutrophil Chemotactic Factor (Interleukin-8) Matsushima et al. (NCI) (17)
Transforming Growth Factor Beta (TGF-beta) Sporn et al. (NIDCR) (19)
Chemokine Receptors Murphy et al. (NIAID) (20)

*for FY 2005, based on royalties on product sales

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