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Calcium Gluconate



Indications and Usage


  • Intravenous calcium gluconate is indicated for Sr-90 contamination, and probably Ra-226 contamination as well.
  • Five ampoules, each containing approximately 500 mg calcium, may be administered in 0.5 liter D5W over a 4- hour period. This treatment may be administered daily for 6 consecutive days.
  • It is contraindicated in patients who have a very slow heart rate, those on digoxin preparations, and those on quinidine.

FDA Product Safety Info

  • Not FDA approved for this indication/off-label use

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References

  1. Marcus, CS. Administration of decorporation drugs to treat internal radionuclide contamination: medical emergency response to radiologic incidents. RSO Magazine, 2004;9(5):9-15. (PDF - 34 KB)
  2. "Radiation Bioterrorism," Tochner ZA, Lehavi O, Glatstein E, Chapter 207 in Harrison's Principles of Internal Medicine, Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL, Jameson JL, eds. 16th Edition, pp 1294-1300, McGraw-Hill, 2005
  3. Management of Persons Accidentally Contaminated with Radionuclides, National Council on Radiation Protection and Measurements, NCRP Report No. 65, Bethesda, MD, 1980.
 

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U.S. Department of Health & Human Services Office of the Assistant Secretary for Preparedness and Response National Library of Medicine