All Type 1 Diabetes Clinical Trials and Clinical Research
Study Name |
Who Can Participate? |
| Type 1 Diabetes TrialNet | |
| This study is no longer recruiting patients. Persons who had developed type 1 (insulin dependent) diabetes within the last three months and who are between the ages of 12 and 35 were eligible to participate.
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| To participate in the screening phase of the Natural History Study, you must be: (1) 1 to 45 years of age and have a brother, sister, child, or parent with type 1 diabetes; OR (2) 1 to 20 years of age and have a cousin, aunt, uncle, niece, nephew, half-sibling, or grandparent with type 1 diabetes.
In general, type 1 diabetes is assumed if it developed before age 40 and required insulin injections within a year of diagnosis.
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This study is no longer recruiting patients. People were eligible for this study if they:
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| This study is no longer recruiting patients. Pregnant women in their third trimester of pregnancy and infants 6 months of age or younger were eligible to enroll if there was a family history of type 1 diabetes.
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| To be screened for the study, you must be: (1) 1 to 45 years of age and have a brother, sister, child, or parent with type 1 diabetes; OR (2) 1 to 20 years of age and have a cousin, aunt, uncle, niece, nephew, half-sibling, or grandparent with type 1 diabetes.
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| To be screened for the abatacept study, research volunteers need to be: (1) 6 to 45 years old; and (2) diagnosed with type 1 diabetes less than 3 months ago. Screening tests, including blood tests, will help decide who can participate in this study. | |
| Search for Diabetes in Youth | |
| Children and youth who are under age 20 when they were diagnosed with diabetes may be eligible to join. Eligibility may depend on the place the child or young adult resides or the place where health care is received.
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| Trial to Reduce IDDM in the Genetically at Risk | |
| Pregnant women who: have type 1 diabetes OR the father of this baby has type 1 diabetes OR a full sibling to this baby has type 1 diabetes.
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| Family Investigation of Nephropathy and Diabetes | |
| In order for a family to participate, there must be at least one person with kidney disease due to diabetes. In addition, there must be at least one full brother/sister (not a half or step brother/sister) who: (1) has diabetes and kidney disease OR (2) has had diabetes for more than 10 years and does not have kidney disease. A family with a member with diabetic kidney disease whose two parents are willing to participate may also be enrolled in the study. Other family members may be recruited to the study as well.
There are also opportunities for Mexican-American patients with diabetic kidney disease, and African-American patients with diabetic and non-diabetic kidney disease and their families to participate as well.
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| Type 1 Diabetes Genetics Consortium | |
| The T1DGC has completed enrollment for the affected sibling pair families phase of the study. We would like to thank all of participants worldwide who helped the study reach this monumental goal.
We are continuing to recruit trios (father, mother, and a child with type 1 diabetes), as well as cases (with type 1 diabetes) and controls (no history of type 1 diabetes) from populations with a low prevalence of the disease only as we have adequate numbers of Caucasians of European origins. In Asia Pacific, this includes individuals from countries such as India and Thailand. In North America, this includes Mexican American and African American individuals.
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| The Environmental Determinants of Diabetes in the Young | |
The Environmental Determinants of Diabetes in the Young (TEDDY) |
A cohort of children with elevated genetic risk for type 1 diabetes will be established by screening newborns from the general population and from families with first-degree relatives diagnosed with type 1 diabetes.
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| Clinical Islet Transplantation Consortium | |
Strategies to Improve Long Term Islet Graft Survival (CIT-02) |
In general, to participate in this study, one must be 18-65 years of age, diagnosed with type 1 diabetes before age 40 and insulin dependent for more than 5 years. There are more specific inclusion and exclusion criterion for participation in this study, which can be discussed with the study contact.
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B-Lymphocyte Immunotherapy in Islet Transplantation (CIT-05) |
In general, to participate in this study, one must be 18-65 years of age, diagnosed with type 1 diabetes before age 40 and insulin dependent for more than 5 years. There are more specific inclusion and exclusion criterion for participation in this study, which can be discussed with the study contact.
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| In general, to participate in this study, one must be 18-65 years of age, diagnosed with type 1 diabetes before age 40, be insulin dependent for more than 5 years, and have received a kidney transplant. There are more specific inclusion and exclusion criterion for participation in this study, which can be discussed with the study contact.
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Peritransplant Deoxyspergualin in Islet Transplantation in Type 1 Diabetes (CIT-03) |
You may be enrolled into this study, if you:
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Islet Transplantation in Type 1 Diabetes with LEA29Y Maintenance Therapy (CIT-04) |
You may be enrolled into this study, if you:
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You may be enrolled into this study, if you:
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