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Eunice Kennedy Shriver National Institute of Child Health and Human Development
Division of Intramural Research

Latest DIR Publication

2007 DIR Annual Report Image

For more, visit the Publications pages.

Bone and Extracellular Matrix Branch

Head: Joan C. Marini

The Bone and Extracellular Matrix Branch conducts research on the extracellular matrix of bone and on diseases resulting from defective matrix. Primary defects of matrix, such as the genetic disorder osteogenesis imperfecta, result in severe osteoporosis and lifelong disability. Laboratory studies are aimed at understanding their genetic etiology and molecular and cellular mechanisms, and will also yield insight into normal skeletal functioning. Clinical protocols of the Branch are focused on improved clinical diagnosis and treatments.

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