Biography
Dr. Pfeiffer was the recipient of a Fulbright Fellowship to study applied statistics in 1992-1993, and received a Ph.D. in mathematical statistics from the University of Maryland, College Park, in 1998. She joined NCI in 1999 as a CRTA fellow. She was appointed as a principal investigator in 2001 and was tenured as a senior investigator in February 2007. Her research focuses on statistical methods for laboratory methods and problems arising in genetic epidemiology.
Research Interests
- Statistical methods for family data accounting for ascertainment
- Mixture models and applications
- Methods for analysis of high dimensional data
- Absolute risk modeling
- Power considerations for association studies
Keywords
genetic epidemiology; ascertainment; family studies; DNA pooling; familial aggregation; mixture models; random effects models; laboratory methods; association studies; absolute risk modeling.
Selected Publications
- Pfeiffer RM, Pee D, Landi MT. On combining family and case-control studies. Genetic Epidemiology. 32:638-46 2008
- Pfeiffer RM, Bura E. A model free approach to combining biomarkers. Biometrical Journal . 50:558-70 2008
- Pfeiffer RM, Mitani A, Matsuno RK, Anderson WF. Racial differences in breast cancer trends in the United States (2000-2004). JNCI. 100:751-2 2008
- Freedman AN, Slattery ML, Ballard-Barbash R, Willis G, Cann BJ, Pee D, Gail MH, Pfeiffer RM. Colorectal Cancer Risk Prediction Tool for White Men and Women Without Known Susceptibility. JCO. Epub ahead of Print, December 29, 2008.
- Park Y, Freedman AN, Gail MH, Pee D, Hollenbeck A, Schatzkin A, and Pfeiffer RM. Validation of a Colorectal Cancer Risk Prediction Model among Whites 50 Years Old and Over. JCO. Epub ahead of Print, December 29, 2008.
- Pfeiffer RM, Carroll RJ, Wheeler W, Whitby D, Mbulaiteye S. Combining assays for estimating prevalence of human herpesvirus 8 infection using multivariate mixture models. Biostatistics, 9(1), pp 137-151, 2008.
