Obsessive-Compulsive Disorder (Pediatric) Research Study
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OCD Sibling Study
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We are examining the causes of Obsessive-Compulsive Disorder (OCD) by looking at the relationship between OCD, the brain, and genetic factors. We are enrolling sibling pairs (ages 8-17) where one sibling has the diagnosis of OCD and the other does not. Siblings must be full siblings (same mother and father).
The 1-day study involves a structured psychiatric interview, psychological testing, a Magnetic Resonance Imaging (MRI) scan, and a brief blood draw. Financial compensation and travel assistance is provided.
To find out if your children qualify or for more information, please call 301-496-0851 or toll-free at 888-254-3823 or email us at sharpw@mail.nih.gov.
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Protocol Information |
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Obsessive-Compulsive Disorder (Pediatric) Research Study
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Riluzole medication treatment of the obsessions and compulsions of Obsessive-Compulsive Disorder
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We are enrolling children or adolescents (ages 7-17 years) who have either:
the repetitive behaviors and compulsions associated with an Autism Spectrum Disorder,
or the obsessions and compulsions of Obsessive-Compulsive Disorder (even without an additional disorder on the autism spectrum).
We are looking for young people who have been treated with adequate doses of medication for their obsessions or repetitive behaviors/compulsions, but who have not had adequate response to treatment, or who could not tolerate the treatment.
We are investigating the medication riluzole. Riluzole is FDA-approved for the treatment of ALS (Lou Gehrig disease).
Participants will receive either riluzole or a placebo (a look-alike pill with no active ingredient) for 12 weeks. At the end of those 12 weeks, all study participants will have the option of taking riluzole (no chance of placebo) for the next 12 weeks.
Participants will have a day-long assessment that includes comprehensive psychiatric, physical, and laboratory evaluations. They will then have follow-up evaluations with the NIMH physician about every month for 6 months, and again at 9 and 12 months. Parental consent is required for study participation. There are no costs to participate in the study. Travel assistance may be provided.
Children must also continue to be followed by their own local physicians while in this outpatient study.
To find out if your child qualifies or for more information, please call (301) 435-6652, (301) 496-5323 or email us at OCDNIMH@intra.nimh.nih.gov.
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Protocol Information |
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