| | Principal Investigators
| Zheng Li, Ph.D. |
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Dr. Zheng Li received a Ph.D. degree from State University of New York at Stony Brook. Her graduate studies were carried out with Hollis Cline at Cold Spring Harbor Laboratory on the role of Rho GTPases in dendrite morphogenesis. She obtained postdoctoral training with Morgan Sheng at Massachusetts Institute of Technology on the molecular and cellular mechanism of synapse development and plasticity. Dr. Li joined NIMH as an Investigator in 2006. Her laboratory uses molecular and cellular biology, live imaging, and electrophysiological approaches to investigate the mechanisms underlying synaptic plasticity in development, cognition and psychiatric disorders, with an emphasis on schizophrenia. |
| Research Interests |
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| Representative Selected Recent Publications: |
- Li Z, Okamoto K, Hayashi Y, and Sheng M:
The importance of dendritic mitochondria for the morphogenesis and plasticity of spines and synapses.
Cell, 119(6), 873-87, 2004.
- Li Z and Sheng M :
Some Assembly Required: the development of neuronal synapses
Nat Rev Mol Cell Biol, 4(11), 833-41, 2003.
- Li Z, Aizeman CD and Cline HT:
Diversity and specificity of actions of Slit2 proteolytic fragments in axon guidance.
Neuron 33(5), 741-50, 2002.
- Haas K, Sin WC, Javaherian A, Li Z, and Cline HT:
Single-cell electroporation for gene transfer in vivo
Neuron 29(3), 583-91, 2001.
- Li Z, Van Aelst L, and Cline HT:
Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo.
Nat Neurosci, 3(3), 217-25, 2000.
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Address:
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Dr. Zheng Li
National Institute of Mental Health
35 Convent Drive,
RM 2C1010, MSC 3732
Bethesda, MD 20892-3732 |
| Phone: |
(301) 594-2269
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| Email Dr. Li |
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| Fax: |
(301) 480-2561 |
| Lab Web Site: |
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