| | Principal Investigators
| Karen Berman, M.D. |
 |
Dr. Berman is
the Chief of the Section on Integrative Neuroimaging in the Clinical Brain Disorders Branch at the NIMH. She completed her medical internship at Washington University in St. Louis and had residency training in psychiatry at the University of California at San Diego. Dr. Berman also completed residency training in nuclear medicine at the NIH Warren G. Magnusen Clinical Center and is board certified in both psychiatry and nuclear medicine. She has received the A.E. Bennett Award for Neuropsychiatric Research of the Society of Biological Psychiatry, the National Alliance for Research on Schizophrenia and Depression (NARSAD) Independent Investigator award, and an NIH Bench to Bedside Award. In 2005, she received the NIH Director’s Award for her outstanding pioneer research on Williams Syndrome. |
| Research Interests |
| Dr. Berman’s group uses functional neuroimaging to map brain activity and neurochemical mechanisms associated with normal higher cognitive function as well as dysfunction in neuropsychiatric illnesses such as schizophrenia, illnesses having genetic sources of cognitive dysfunction such as Williams syndrome, and other conditions impacting cognition such as normal aging. They also study the effects of gonadal steroid hormones on brain function. |
| Representative Selected Recent Publications: |
- Buchsbaum BR, Olsen RK, Kock P, Berman KF: Human dorsal and ventral auditory streams subserve rehearsal-based and echoic processes during verbal working memory. Neuron, 48: 687-697, 2005.
- Kippenhan JS, Olsen RK, Mervis CB, Morris CA, Kohn P, Meyer-Lindenberg A, Berman ,KF: Genetic contributions to human gyrification: sulcal morphometry in Williams Syndrome. J Neurosci, 25: 7840-7846, 2005. (View PDF)
- Meyer-Lindenberg A, Hariri AR, Munoz KE, Mervis CB, Mattay VS, Morris CA, Berman KF: Neural correlates of genetically abnormal social cognition in Williams syndrome. Nat Neurosci, 8: 991-993, 2005. (View PDF)
- Meyer-Lindenberg A, Kohn PD, Kolachana B, Kippenhan S, McInerney-Leo A, Nussbaum R, Weinberger DR, Berman KF: Midbrain dopamine and prefrontal function in humans: interaction and modulation by COMT genotype. Nat Neurosci, 8: 594-596, 2005. (View PDF)
- Meyer-Lindenberg A, Kohn P, Mervis CB, Kippenhan JS, Olsen RK, Morris CA, Berman KF: Neural basis of genetically determined visuospatial construction deficit in Williams syndrome. Neuron, 43: 623-631, 2004. (View PDF)
- Meyer-Lindenberg A, Miletich RW, Kohn P, Esposito G, Carson RE, Quarantelli M, Weinberger DR, Berman KF: Reduced prefrontal activity predicts exaggerated striatal dopamine function in schizophrenia. Nat Neurosci, 5: 267-271, 2002. (View PDF)
|
|
|
|
|
