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Our Science – Gildersleeve Website

Jeffrey C. Gildersleeve, Ph.D.

Selected Publications
1)  Gildersleeve JC, Oyelaran O, Simpson JT, Allred B.
Improved procedure for direct coupling of carbohydrates to proteins via reductive amination.
Bioconjug. Chem. 19: 1485-90, 2008. [Journal]
2)  Li Z, Gildersleeve J.
An Armed-Disarmed Approach for Blocking Aglycon Transfer of Thioglycosides.
Tetrahedron Letters. 48: 559-562, 2007. [Journal]
3)  Manimala JC, Roach TA, Li Z, Gildersleeve JC.
Supplier-dependent anti-glycan monoclonal antibody specificities: Comment on.
Glycobiology. 2008. [Journal]
4)  Hsu KL, Gildersleeve JC, Mahal LK.
A simple strategy for the creation of a recombinant lectin microarray.
Mol Biosyst. 4: 654-62, 2008. [Journal]
5)  Oyelaran O, Gildersleeve JC.
Application of carbohydrate array technology to antigen discovery and vaccine development.
Expert review of vaccines. 6: 957-69, 2007. [Journal]
6)  Manimala JC, Roach TA, Li Z, Gildersleeve JC.
High-Throughput Carbohydrate Microarray Profiling of 27 Antibodies Demonstrates Widespread Specificity Problems.
Glycobiology. 2007. [Journal]
7)  Li Z, Gildersleeve JC.
Mechanistic studies and methods to prevent aglycon transfer of thioglycosides.
J. Am. Chem. Soc. 128: 11612-9, 2006. [Journal]
8)  Manimala JC, Roach TA, Li Z, Gildersleeve JC.
High-Throughput Carbohydrate Microarray Analysis of 24 Lectins.
Angew Chem Int Ed Engl. 2006. [Journal]
9)  Manimala JC, Li Z, Jain A, VedBrat S, Gildersleeve JC.
Carbohydrate Array Analysis of Anti-Tn Antibodies and Lectins Reveals Unexpected Specificities: Implications for Diagnostic and Vaccine Development.
Chembiochem. 6: 2229-2241, 2005. [Journal]
10)  Kagan E, Ragupathi G, Yi SS, Reis CA, Gildersleeve J, Kahne D, Clausen H, Danishefsky SJ, Livingston PO.
Comparison of antigen constructs and carrier molecules for augmenting the immunogenicity of the monosaccharide epithelial cancer antigen Tn.
Cancer Immunol Immunother. 54: 424-30, 2005. [Journal]
11)  Zhang Z, Gildersleeve J, Yang YY, Xu R, Loo JA, Uryu S, Wong CH, Schultz PG.
A new strategy for the synthesis of glycoproteins.
Science. 303: 371-3, 2004. [Journal]
12)  Gildersleeve J, Varvak A, Atwell S, Evans D, Schultz PG.
Development of a High-Throughput Screen for Protein Catalysts: Application to the Directed Evolution of Antibody Aldolases.
Angew Chem Int Ed Engl. 42: 5971-5973, 2003. [Journal]
13)  Gildersleeve J, Janes J, Ulrich H, Yang P, Barbas C, Schultz PG.
Development of a genetic selection for catalytic antibodies.
Bioorg Med Chem Lett. 12: 1691-4, 2002. [Journal]
14)  Xuereb H, Maletic A, Gildersleeve J, Pelczer I, Kahn D.
Design of an Oligosaccharide Scaffold that Binds in the Minor Groove of DNA.
J. Am. Chem. Soc. 122: 1883-1890, 2000. [Journal]
15)  Gildersleeve J, Smith A, Sakurai K, Raghavan S, K D.
Scavenging Byproducts in the Sulfoxide Glycosylation Reaction: Application to the Synthesis of Ciclamycin 0.
J. Am. Chem. Soc. 121: 6176-6182, 1999. [Journal]
16)  Gildersleeve J, Pascal R, Kahn D.
Sulfenate Intermediates in the Sulfoxide Glycosylation Reaction.
J. Am. Chem. Soc. 120: 5961-5969, 1998. [Journal]
17)  Liang R, Yan L, Loebach J, Ge M, Uozumi Y, Sekanina K, Horan N, Gildersleeve J, Thompson C, Smith A, Biswas K, Still WC, Kahne D.
Parallel synthesis and screening of a solid phase carbohydrate library.
Science. 274: 1520-2, 1996. [Journal]

This page was last updated on 9/25/2008.