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Home : Kidney & Urologic Diseases A-Z List of Topics and Titles : Kidney Disease in Children : Treatment Methods for Kidney Failure in Children

 

Treatment Methods for Kidney Failure in Children

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Kidneys play an important part in a child's growth and health. They

  • remove wastes and extra water from the blood
  • regulate blood pressure
  • balance chemicals like sodium and potassium
  • make a hormone that signals bone marrow to make red blood cells
  • make a hormone to help bones grow and keep them strong

Kidney failure can lead directly to more health problems, like swelling of the body, bone deformities, and growth failure. A successful kidney transplant can give a child with chronic kidney failure the best chance to grow normally and lead a full, active life. Dialysis can help a child to survive an acute episode of kidney failure or to stay healthy until a donated kidney becomes available.

Families caring for a child with kidney disease often need help—not just from doctors and nurses, but from a whole team of pediatric specialists, including dietitians, social workers, and family counselors. Learning about treatments for kidney disease and getting to know the entire team can make life easier for your child and your entire family.

Illustration of young boy with a diagram of the location of the kidneys, ureters, and bladder
The kidneys remove wastes and extra water from the blood to form urine. Urine flows from the kidneys to the bladder through the ureters.

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Problems Specific to Children

Everyone who has kidney failure, adults and children alike, will experience medical complications, which may include extreme fatigue, inability to concentrate, weak bones, nerve damage, depression, and sleep problems. Additional problems for children can include effects on their growth and development. Children may fall behind on the growth chart and in school.

The isolation people feel because of kidney failure is especially a problem in children and adolescents because of the importance of making friends and fitting in at this age. Finding the best treatment for a child takes on special significance to ensure that the child with kidney failure can become an active, productive, well-adjusted adult.

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Treatment Choices for Kidney Failure in Children

Children usually have a range of treatment options for kidney failure. In most cases, the goal is to have a successful transplant that allows your child to lead the most normal life possible. But viable kidneys are not always readily available, and not all children can have a transplant. Many children begin with dialysis to stay healthy until a suitable kidney becomes available. Sometimes, a transplant itself may stop working, and the child may need to return to dialysis. Knowing about transplantation and dialysis will prepare you and your child for any circumstance.

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Transplantation

Transplantation means that a healthy kidney from a donor is placed inside a child's body to take over the job of filtering wastes and extra fluid from the blood. The donor may be a stranger who has just died or a living family member or friend.

Once kidneys fail because of chronic kidney disease, function cannot be restored, so transplantation is the closest thing to a cure we have. A child with a transplant will still need to take medicines every day, follow a restricted diet, and get regular checkups to make sure the new kidney is accepted and functioning in the body.

In adults, most transplanted kidneys come from people who have just died. However, about half of the kidney transplants in children come from a living donor, usually a parent or other close family member.

Kidney Transplant
Kidney transplantation

Deceased Donor Kidneys
To receive a deceased donor kidney, your child will be placed on a waiting list. Every person who needs an organ from a deceased donor is registered with the United Network for Organ Sharing (UNOS), which maintains a centralized computer network linking all regional organ gathering organizations and transplant centers. (See Resources.)

How long your child will have to wait for a transplant depends on many things but is determined primarily by how good the match is between your child and a donor. When a kidney becomes available, the hospital that has obtained the kidney reports to UNOS, where the central computer generates a list of compatible recipients. Candidates' ages and length of time they have waited are factors in the point system. Children 18 and under get extra points compared with adults because they are likely to receive the greatest benefit from a donated kidney.

While your child is on the waiting list, notify the transplant center of any changes in health status, address, or phone number. The center will need to find you immediately when a kidney becomes available.

Living Donor Kidneys
About half of the kidneys transplanted into children are donated by family members—usually a parent—or a family friend. Potential donors need to be tested for matching factors and to make sure that donating a kidney will not endanger their health. Most people can donate a kidney with little risk.

A kidney from a living donor often has advantages over a kidney from a person who has just died.

  • A kidney from a parent is guaranteed to match on at least three of six proteins; mismatched proteins may cause rejection.

  • Living donation allows for greater preparation and for the operation to be scheduled.

  • A kidney from a living donor may be in better condition because it does not have to be transported from one site to another.

Preemptive Transplantation
Preemptive transplantation means that the child receives a donated kidney before dialysis is needed. Some studies indicate that preemptive transplantation reduces the chances of rejecting the new kidney and improves the chances that it will function for a long time. Other studies show little or no survival advantage in preemptive transplants, although some families may feel that avoiding dialysis is an advantage in itself.

Keeping a Healthy Kidney
Health professionals use the term "noncompliance" or "nonadherence" to describe a patient's failure or refusal to take prescribed medicines or follow a doctor's directions. Teenagers with transplanted organs are often noncompliant because the immunosuppressive drugs they must take change their appearance in unflattering ways. A child psychologist may be able to suggest techniques that reinforce desired behaviors. But communicating clearly about the reasons for treatment and the importance of following the regimen is an important part of helping all patients, including children. Children who understand that their decisions can affect their health are more likely to take responsibility for their actions.

For more information about transplantation procedures, see the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) booklet Treatment Methods for Kidney Failure: Transplantation.

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Dialysis

The kidneys remove waste products and extra water from the blood. If the kidneys fail before transplantation is possible, your child may need some form of dialysis to do this job. Each type of dialysis will affect your family's lifestyle. Your doctor will help you choose the one that is best for your child. Each situation is different.

Peritoneal Dialysis
Peritoneal dialysis uses the lining of your child's abdomen, called the peritoneal membrane, to filter blood. A mixture of minerals and sugar dissolved in water, called dialysis solution, is inserted into your child's abdomen through a soft tube. The sugar, called dextrose, draws wastes, chemicals, and extra water from the tiny blood vessels in the peritoneal membrane into the dialysis solution. After some time, the used solution—now loaded with the wastes and extra fluid that the kidneys would have filtered out—is drained from your child's abdomen through the tube. The period that dialysis solution is in the abdomen is called the dwell time. The abdomen is filled again with fresh dialysis solution, and the cycle repeats. The process of emptying and refilling the abdomen is called an exchange and takes about 30 to 40 minutes.

Before the first treatment, a surgeon will place a small, soft tube called a catheter into your child's abdomen. The catheter tends to work better if the insertion site has time—usually from 10 days to 3 weeks—to heal. The catheter stays there to help transport dialysis solution to and from the abdomen and is removed only after a successful transplant is in place.

Peritoneal dialysis
Peritoneal dialysis

Peritoneal dialysis can be done with or without a cycling machine.

  • Continuous ambulatory peritoneal dialysis (CAPD). CAPD requires no machine and can be done in any clean, well-lit place. With CAPD, your child's blood is always being cleaned. The dialysis solution passes from a plastic bag through the catheter and into the abdomen, where it stays for several hours with the catheter sealed. After the dwell time, the child drains the dialysis solution into a drain bag for disposal. Then the same catheter is used to refill the abdomen with fresh solution so the cleaning process can begin again. With CAPD, the dialysis solution stays in the abdomen for 4 to 6 hours or more. Most people change the dialysis solution at least four times a day and sleep with solution in their abdomen at night. With CAPD, it is not necessary to perform an exchange during the night.

  • Continuous cycling peritoneal dialysis (CCPD). CCPD uses a machine called a cycler to fill and empty your child's abdomen many times at night during sleep. In the morning, the child begins one exchange with a dwell time that lasts the entire day. An additional exchange without the cycler may be added in the middle of the afternoon to increase the amount of waste removed and to reduce the amount of fluid left behind.

Both types of peritoneal dialysis can be performed in the home without help from a nurse or doctor. If your child is very young, you will need to help with the exchanges or set up the cycler. Older children can do it themselves. You and your child will receive detailed instructions and extensive training so you feel confident when you perform the exchanges.

The most common problem with peritoneal dialysis is peritonitis, a serious abdominal infection that can occur if the opening where the catheter enters the body becomes infected or if contamination occurs as the catheter is connected or disconnected from the bags. Peritonitis requires antibiotic treatment prescribed by your child's nephrologist.

To avoid peritonitis, you must be careful to follow the correct procedures exactly and learn to recognize the early signs—fever, unusual color or cloudiness of the used fluid, and redness or pain around the catheter. Report these signs to your child's doctor immediately so treatment for infection can begin promptly.

For more information about peritoneal dialysis, see the NIDDK booklet Treatment Methods for Kidney Failure: Peritoneal Dialysis.

Hemodialysis
In hemodialysis, your child’s blood is sent through a filter to remove harmful wastes, extra salt, and extra water. Hemodialysis helps control blood pressure and keep the proper balance of potassium, sodium, calcium, and bicarbonate.

Hemodialysis uses a special filter called a dialyzer. During treatment, blood travels from the child's body through tubes into the dialyzer, which filters out wastes and extra water. Then the cleaned blood flows through another set of tubes back into the child's body. The dialyzer is connected to a machine that monitors blood flow and disposes of the wastes.

Hemodialysis usually takes place in a clinic three times a week, but it may be required more often in smaller children. Each treatment lasts from 3 to 4 hours. Some clinics offer home hemodialysis, which allows more flexibility in scheduling but requires the caregiver to take weeks of training. During treatment, the child can do homework, read, write, sleep, talk, or watch TV.

If you choose hemodialysis, the doctor will need to create an access to the bloodstream (vascular access) several months before the first treatment. The child may be able to complete the procedure for the vascular access in one day or may need to stay overnight in the hospital.

For more information, see the NIDDK fact sheet Vascular Access for Hemodialysis.

When a child starts hemodialysis, problems can be caused by rapid changes in the body's water and chemical balance during treatment. Muscle cramps and a sudden drop in blood pressure are two common side effects. Low blood pressure, called hypotension, can make a child feel weak, dizzy, or nauseated.

Most children need a few months to adjust to hemodialysis. Side effects can often be treated quickly and easily, so you should always report them to your doctor and dialysis staff. You can avoid many side effects by making sure your child gets a proper diet, limits liquid intake, and takes all medicines as directed. See Role of the Health Care Team—Dietitian for more information on how the right food choices can help.

For more information about hemodialysis, see the NIDDK booklet Treatment Methods for Kidney Failure: Hemodialysis.

Illustration of teenage boy receiving hemodialysis. The boy is sitting in a chair next to the hemodialysis machine with two tubes attached to his arm. Unfiltered blood flows from the boy's arm to the hemodialyzer (where filtering takes place). Then filtered blood flows from the hemodialyzer back to the boy's body.
Hemodialysis

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Role of the Health Care Team

Because the treatments for kidney failure involve complicated procedures with a number of steps, many skilled professionals must work together to ensure that your child gets the best possible care. As a parent or guardian, you are the most important member of your child's team. You may need to speak for your child or ask questions when instructions are not clear. Knowing the roles of the different team members can help you ask the right questions and contribute to your child's care.

Pediatrician
A pediatrician is a doctor who treats children. Your child's pediatrician is likely to be the first to recognize a kidney problem—either during a routine physical exam or while treating an ailment. Depending on how well the kidneys are working, the doctor may decide to monitor your child or advise you to see a specialist. (Your health insurance plan may require a written referral from the pediatrician in order for you to make an appointment with a specialist.) As your child's regular doctor, the pediatrician should talk with any specialists who become involved. A referral for consultation should optimally occur soon after chronic kidney disease is diagnosed, even if dialysis and transplantation are still a long way off.

Nephrologist
A nephrologist is a doctor who treats kidney diseases and kidney failure. If possible, your child should see a pediatric nephrologist because they are specifically trained to take care of kidney problems in children. In many areas of the country, pediatric nephrologists are in short supply, so you and your child may need to travel. If traveling is not possible, some nephrologists who treat adults can also treat children in consultation with a pediatric nephrologist.

The nephrologist may prescribe treatments to slow disease progression and will determine when referral to a transplant center or to a dialysis clinic is appropriate.

Dialysis Nurse
If your child needs dialysis, a nurse with special training will make sure all procedures are followed carefully. If you and your child choose peritoneal dialysis, the dialysis nurse will train you so you feel comfortable doing the exchanges at home. For hemodialysis in a clinic, the dialysis nurse will make sure that all needles are placed correctly and watch for any problems. The dialysis nurse can talk to you about the advantages and disadvantages of the different types of dialysis and explain the laboratory reports that indicate how well the treatments are working.

Transplant Coordinator
A coordinator at the transplantation center will be your main contact. He or she will schedule any required examinations and procedures and make sure your child's medical information is complete and properly placed on the UNOS national waiting list. The transplant coordinator will make sure that every member of the child's health care team has all the necessary information and paperwork.

Social Worker
Every dialysis clinic and transplant center has a social worker who can help you locate financial assistance and social services like transportation or family counseling and help with applications for Medicare. The social worker can tell you about support groups in your community and ways to reduce the stress that caring for a child with a chronic illness can cause.

Psychologist, Psychiatrist, or Counselor
Kidney disease can disrupt a child's life and create emotional turmoil. A psychologist or counselor can help your child find ways to express emotions constructively. Adults and siblings may also find that counseling helps them with the conflicts and stresses they face. For example, medical bills can strain family finances. A parent or guardian may need to give up work to care for the child full-time. Siblings may feel resentment over the huge amount of attention given to their sibling and guilt over thinking bad thoughts about the sick child. Couples sometimes report increased tension in their marriage when a child is sick. A counselor can help families deal with conflicts that may arise, and social workers or financial counselors can help families meet the financial obligations that chronic illness creates.

Dietitian
When the kidneys stop working, wastes and excess fluid build up in the body and create chemical and hormonal imbalances. In children, however, these problems are especially troublesome because they can interfere with physical growth and mental development. Avoiding certain foods can help minimize the buildup of wastes and prevent chemical imbalance, but it can also lead to nutritional deficiencies. The buildup of wastes often makes children lose their appetite, causing further nutritional problems. These complications are the reason your clinic's dietitian is so important.

Proper nutrition is extremely important for children with chronic kidney disease. Every dialysis clinic has a dietitian to help patients understand how the food they eat affects their health. The dietitian can help you develop meal plans that will fit your child's restricted diet and will talk with you about laboratory reports that may show nutritional deficiencies caused by your child's kidney disease. They may recommend special dietary supplements or formulas so that your child receives the best nutrition possible.

You can also ask your dietitian for recipes and titles of cookbooks for patients with kidney disease. Following the restrictions of a kidney disease diet might be hard at first, but with a little creativity, you can make tasty and satisfying meals. Reading Eat Right to Feel Right on Hemodialysis, a booklet from the NIDDK, can help you get started.

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Vaccinations and Immunosuppression

The wastes and toxins that build up in the bloodstream of a child with kidney disease can weaken the immune system and make the child vulnerable to infections and the kinds of diseases that vaccines are designed to prevent. Children with kidney failure should receive the standard vaccinations recommended for all children, plus additional vaccinations for pneumonia and influenza.

Children who take immunosuppressive medication to treat an autoimmune disease or to prevent rejection of a transplanted kidney, however, should not receive vaccines containing live viruses, that is, the oral polio vaccine, the measles, mumps, and rubella (MMR) vaccine, or the varicella (chicken pox) vaccine. Children who are likely to need a transplant may benefit from early immunization with these vaccines before immunosuppressive drugs are needed.

The body's immune system protects against foreign substances like bacteria and viruses that can cause disease. But the immune system also attacks transplanted organs, and the medicines that recipients must take to prevent rejection leave them vulnerable to infections. Children need relatively higher doses of immunosuppressive drugs than adults because their immune systems are more active. But these high doses can slow down growth and development. Over a long period of time, immunosuppression may lead to malignant growths. Immunosuppressive drugs can also have side effects such as weight gain, unusual hair growth, and acne. Children, especially teenagers, cite these side effects as the reason they do not take their pills, a problem that contributes to the high rate of organ rejection in children.

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Medical Complications of Kidney Failure

The kidneys not only clean waste and extra fluid from the blood, they also help make red blood cells and balance nutrients needed for strong bones and growth. In addition, the kidneys may play a role in the metabolism of growth hormone (somatotropin). Chronic kidney disease can make children feel more tired, limit physical growth, and interfere with their ability to concentrate in school.

Anemia

Diseased kidneys do not make enough of a hormone called erythropoietin, or EPO, which stimulates the bone marrow to produce the red blood cells needed to carry oxygen to vital organs. Anemia is a shortage of red blood cells, and it is common in children with kidney disease. A child with anemia may tire easily and look pale. Anemia may also contribute to heart problems. A genetically engineered form of EPO injected under the skin one or more times a week can treat this form of anemia.

For more information, see the NIDDK fact sheet Anemia in Kidney Disease and Dialysis.

Bone Problems and Growth Failure

The kidneys help keep bones healthy by balancing phosphorus and calcium levels in the blood. When the kidneys stop working normally, phosphorus levels in the blood can become high and interfere with bone formation and normal growth.

Your child's doctor may recommend dietary changes and food supplements to treat growth failure. Dietary changes may include limiting foods that contain large amounts of phosphorus, such as milk, cheese, cola, dried beans, peas, and nuts. Since avoiding all of these foods is impossible, caregivers will need to work with a dietitian to find a healthy way to limit the phosphorus in the child's diet while maintaining a desirable intake of the calories, protein, and other nutrients necessary to maintain growth and general health. In addition to dietary restrictions, most children will need to take specific medications called phosphate binders to lower their blood phosphorus levels.

For more information, see the NIDDK fact sheet Growth Failure in Children With Kidney Disease.

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Financial Help for Treatment of Kidney Failure

No matter what treatment method your family chooses, medical expenses will be high. Fortunately, the Federal Government and many other organizations offer programs to help with the cost of treatments.

Medicare

In 1972, Congress passed legislation making people with permanent kidney failure, no matter what their age, eligible for Medicare, a program that helps people over 65 and people with disabilities pay for medical care.

Role of the Social Worker

Your child's dialysis or transplant center has a social worker who can help you apply for Medicare and locate other sources of financial assistance. For more information about Medicare and other organizations that can help, see the NIDDK fact sheet Financial Help for Treatment of Kidney Failure.

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Hope through Research

Through its Division of Kidney, Urologic, and Hematologic Diseases, the NIDDK supports several programs and studies devoted to improving treatment for patients with progressive kidney disease and kidney failure. The NIDDK maintains the Pediatric Nephrology Program, which supports research into the causes, treatment, and prevention of kidney diseases in children, including congenital malformations of the urinary tract, polycystic disease, primary glomerular disease, and postinfection glomerulonephritis.

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Resources

Websites

Several agencies and organizations maintain informative websites for people with kidney disease. The following sites are designed specifically for children and their parents or guardians:

MEDLINEplus: Kidney Diseases (General)
www.nlm.nih.gov/medlineplus/kidneydiseases.html

The National Library of Medicine maintains MEDLINEplus, a resource providing health information for consumers. The page on kidney diseases contains links to news articles and fact sheets about kidney diseases under many headings, including "Children."

The Nemours Foundation's KidsHealth.org
http://kidshealth.org/parent/medical/kidney/chronic_kidney_disease.html

http://kidshealth.org/kid/feel_better/things/dialysis.html

The Nemours Foundation supports children's hospitals in Delaware and Florida. The KidsHealth website includes articles on many health topics written for parents, teenagers, and young children. The pages listed above contain "When Your Child Has a Chronic Kidney Disease" and "What's the Deal With Dialysis?"—an article written for children. You can click on "Related Articles" and find several more KidsHealth pages devoted to kidney diseases and their treatments.

National Kidney Foundation: Children With Chronic Kidney Diseases: Tips for Parents
www.kidney.org/atoz/atozItem.cfm?id=52

The National Kidney Foundation has developed many programs to help support and educate patients and their families. This page contains "Children With Chronic Kidney Disease: Tips for Parents," which is also available in brochure form (see Additional Reading).

Kidney Directions: KD Kids
www.renalinfo.com/us/

The Kidney Directions website was developed by a manufacturer of dialysis equipment. The KD Kids page offers information for parents and children about kidney disease and its complications.

Nephkids Cyber-Support Group for Parents of Children With Kidney Disease
http://cnserver0.nkf.med.ualberta.ca/nephkids

Nephkids is a listserv, an interactive email group for parents of children with various chronic kidney diseases.

Organizations

Several groups offer information and services to patients with kidney disease. You may wish to contact one of the following:

American Association of Kidney Patients
3505 East Frontage Road
Suite 315
Tampa, FL 33607
Phone: 1–800–749–2257 or 813–636–8100
Email: info@aakp.org
Internet: www.aakp.org

American Kidney Fund
6110 Executive Boulevard
Suite 1010
Rockville, MD 20852
Phone: 1–800–638–8299 or 301–881–3052
Email: helpline@kidneyfund.org
Internet: www.kidneyfund.org

American Society of Pediatric Nephrology
Northwestern University
Feinberg School of Medicine
Pediatrics W140
303 East Chicago Avenue
Chicago, IL 60611–3008
Phone: 312–503–4000
Email: aspn@northwestern.edu
Internet: www.aspneph.com

Life Options Rehabilitation Program
c/o Medical Education Institute Inc.
414 D'Onofrio Drive
Suite 200
Madison, WI 53719
Phone: 1–800–468–7777 or 608–232–2333
Email: lifeoptions@MEIresearch.org
Internet: www.lifeoptions.org and www.kidneyschool.org

National Kidney Foundation
30 East 33rd Street
New York, NY 10016
Phone: 1–800–622–9010 or 212–889–2210
Email: info@kidney.org
Internet: www.kidney.org

United Network for Organ Sharing
P.O. Box 2484
Richmond, VA 23218
Phone: 1–888–894–6361
Internet: www.unos.org

Additional Reading

If you would like to learn more about kidney failure and its treatment, you may be interested in reading these publications:

Adventure at Riverside Park: A Story About Pediatric Dialysis
This story describes a young girl's experiences and emotions as a peritoneal dialysis patient. The book introduces the members of the health care team and explains the role each plays in dialysis treatment.

National Kidney Foundation of Indiana, Inc.
850 North Meridian Street
Suite 203
Indianapolis, IN 46204–1108
Phone: 1–800–382–9971
Internet: www.kidneyindiana.org

Children With Chronic Kidney Disease: Tips for Parents
Nutrition and Peritoneal Dialysis

National Kidney Foundation
30 East 33rd Street
New York, NY 10016
Phone: 1–800–622–9010 or 212–889–2210
Internet: www.kidney.org

Kidney Disease in Children
Kidneys for Kids
“The Kid,”
a booklet written for children with kidney disease
Diet Guide for the CAPD Patient
American Kidney Fund
6110 Executive Boulevard
Suite 1010
Rockville, MD 20852
Phone: 1–800–638–8299 or 301–881–3052
Email: helpline@kidneyfund.org
Internet: www.kidneyfund.org

Medicare Coverage of Kidney Dialysis and Kidney Transplant Services
Publication Number CMS–10128
U.S. Department of Health and Human Services
Centers for Medicare & Medicaid Services
7500 Security Boulevard
Baltimore, MD 21244–1850
Phone: 1–800–MEDICARE (1–800–633–4227)
TDD: 1–877–486–2048
Internet: www.medicare.gov

Financing Transplantation: What Every Patient Needs to Know, 2nd edition, 1996
United Network for Organ Sharing
P.O. Box 2484
Richmond, VA 23218
Phone: 1–888–894–6361 to order single copies
             804–782–4841 to order bulk copies
Internet: www.unos.org

Newsletters and Magazines

Family Focus Newsletter (published quarterly)
National Kidney Foundation
30 East 33rd Street
New York, NY 10016
Phone: 1–800–622–9010 or 212–889–2210
Internet: www.kidney.org

For Patients Only Magazine (published six times a year)
20335 Ventura Boulevard
Suite 400
Woodland Hills, CA 91364
Phone: 818–704–5555

Renalife Magazine (published quarterly)
American Association of Kidney Patients
3505 East Frontage Road
Suite 315
Tampa, FL 33607
Phone: 1–800–749–2257 or 813–636–8100
Email: help@aakp.org
Internet: www.aakp.org

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Additional Information on Treatment Methods for Kidney Failure in Children

The National Kidney and Urologic Diseases Information Clearinghouse collects resource information on kidney and urologic diseases for the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Reference Collection. This database provides titles, abstracts, and availability information for health information and health education resources. The NIDDK Reference Collection is a service of the National Institutes of Health.

To provide you with the most up-to-date resources, information specialists at the clearinghouse created an automatic search of the NIDDK Reference Collection. To obtain this information, you may view the results of the automatic search on Treatment Methods for Kidney Failure in Children.

If you wish to perform your own search of the database, you may access and search the NIDDK Reference Collection database online.

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National Kidney and Urologic Diseases Information Clearinghouse

3 Information Way
Bethesda, MD 20892–3580
Phone: 1–800–891–5390
TTY: 1–866–569–1162
Fax: 703–738–4929
Email: nkudic@info.niddk.nih.gov
Internet: www.kidney.niddk.nih.gov

The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The NIDDK is part of the National Institutes of Health of the U.S. Department of Health and Human Services. Established in 1987, the Clearinghouse provides information about diseases of the kidneys and urologic system to people with kidney and urologic disorders and to their families, health care professionals, and the public. The NKUDIC answers inquiries, develops and distributes publications, and works closely with professional and patient organizations and Government agencies to coordinate resources about kidney and urologic diseases.

Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts. The NKUDIC would like to thank Barbara Fivush, M.D., and Kathy Jabs, M.D., of the American Society of Pediatric Nephrology (ASPN), for coordinating the review of this fact sheet by the ASPN’s Clinical Affairs Committee: Tej Mattoo, M.D., William Primack, M.D., Joseph Flynn, M.D., Ira Davis, M.D., Ann Guillott, M.D., Steve Alexander, M.D., Deborah Kees-Folts, M.D., Alicia Neu, M.D., Steve Wassner, M.D., John Brandt, M.D., Manju Chandra, M.D. Frederick Kaskel, M.D., Ph.D., President, ASPN, and Sharon Andreoli, M.D., Secretary–Treasurer, ASPN, also provided comments and coordination.

This publication is not copyrighted. The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired.


NIH Publication No. 06–5082
April 2006

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National Kidney and Urologic Diseases Information Clearinghouse
3 Information Way
Bethesda, MD 20892–3580
Phone: 1–800–891–5390
TTY: 1–866–569–1162
Fax: 703–738–4929
Email: nkudic@info.niddk.nih.gov

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