| Year: 2006 | 
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| LHNCBC-2006-009 |
| Experience in Reasoning with the Foundational Model of Anatomy in OWL DL |
| Zhang S, Bodenreider O, Golbreich C |
| In: Altman RB, Dunker AK, Hunter L, Murray TA, Klein TE, editors. Pacific Symposium on Biocomputing 2006: World Scientific; 2006. p. 200-211. |
| The objective of this study is to compare description logics (DLs) and frames for representing large-scale biomedical ontologies and reasoning with them. The ontology under investigation is the Foundational Model of Anatomy (FMA). We converted it from its frame-based representation in Protege into OWL DL. The OWL reasoner Racer helped identify unsatisfiable classes in the FMA. Support for consistency checking is clearly an advantage of using DLs rather than frames. The interest of reclassification was limited, due to the difficulty of defining necessary and sufficient conditions for anatomical entities. The sheer size and complexity of the FMA was also an issue. |
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