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Ther Clin Risk Manag. 2008 June; 4(3): 641–644.
Published online 2008 June.
PMCID: PMC2500258
Efficacy of deoxyspergualine for antibody-mediated rejection and proteinuria after kidney transplantation
Hideki Ishida and Kazunari Tanabe
Department of Urology, Tokyo Women’s Medical University, Tokyo, Japan
Correspondence: Hideki Ishida Department of Urology, Tokyo Women’s Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, Japan, 162-8666 Tel+ 81 3 3353 8111 ex 39112 Fax +81 3 3356 0293 Email tgphide/at/gol.com
Abstract
A patient showing antibody-mediated rejection (AMR) with severe vasculitis, and massive proteinuria after kidney transplantation was treated with deoxyspergualine (DSG, Spanidin®, Nippon Kayaku). DSG showed marked efficacy for this patient’s symptoms. We report on a patient for whom DSG was effective against AMR after renal transplantation.
Keywords: deoxyspergualine (DSG), vascular rejection, antihuman leukocyte antigen (HLA) antibody